关键词: aortic aneurysm computational fluid dynamics extracorporeal membrane oxygenation heart valve

来  源:   DOI:10.1177/02676591241239277

Abstract:
Cardiovascular diseases persist as a leading cause of mortality and morbidity, despite significant advances in diagnostic and surgical approaches. Computational Fluid Dynamics (CFD) represents a branch of fluid mechanics widely used in industrial engineering but is increasingly applied to the cardiovascular system. This review delves into the transformative potential for simulating cardiac surgery procedures and perfusion systems, providing an in-depth examination of the state-of-the-art in cardiovascular CFD modeling. The study first describes the rationale for CFD modeling and later focuses on the latest advances in heart valve surgery, transcatheter heart valve replacement, aortic aneurysms, and extracorporeal membrane oxygenation. The review underscores the role of CFD in better understanding physiopathology and its clinical relevance, as well as the profound impact of hemodynamic stimuli on patient outcomes. By integrating computational methods with advanced imaging techniques, CFD establishes a quantitative framework for understanding the intricacies of the cardiac field, providing valuable insights into disease progression and treatment strategies. As technology advances, the evolving synergy between computational simulations and clinical interventions is poised to revolutionize cardiovascular care. This collaboration sets the stage for more personalized and effective therapeutic strategies. With its potential to enhance our understanding of cardiac pathologies, CFD stands as a promising tool for improving patient outcomes in the dynamic landscape of cardiovascular medicine.
摘要:
心血管疾病仍然是死亡和发病的主要原因,尽管诊断和手术方法取得了重大进展。计算流体动力学(CFD)代表流体力学的一个分支,广泛应用于工业工程,但越来越多地应用于心血管系统。这篇综述深入研究了模拟心脏手术程序和灌注系统的变革潜力,提供对心血管CFD建模的最先进水平的深入研究。该研究首先描述了CFD建模的基本原理,后来重点介绍了心脏瓣膜手术的最新进展,经导管心脏瓣膜置换术,主动脉瘤,和体外膜氧合.这篇综述强调了CFD在更好地理解病理生理学及其临床相关性方面的作用。以及血液动力学刺激对患者预后的深远影响。通过将计算方法与先进的成像技术相结合,CFD建立了一个定量框架来理解心脏场的复杂性,为疾病进展和治疗策略提供有价值的见解。随着技术的进步,计算模拟和临床干预之间不断发展的协同作用有望彻底改变心血管护理。这种合作为更个性化和有效的治疗策略奠定了基础。它有可能增强我们对心脏病的理解,CFD是改善心血管医学动态环境中患者预后的有前途的工具。
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