Abstract：
Gut microbes are known to impact host physiology in several ways. However, key molecular players in host-commensal interactions remain to be uncovered. In this issue of Cell, McCurry et al. reveal that gut bacteria perform 21-dehydroxylation to convert abundant biliary corticoids to neurosteroids using readily available H2 in their environment.
摘要：
已知肠道微生物以多种方式影响宿主生理学。然而,宿主-共生相互作用中的关键分子参与者仍有待发现。在本期《细胞》中,McCurry等人。揭示了肠道细菌在其环境中使用容易获得的H2进行21-脱羟基作用以将丰富的胆汁皮质激素转化为神经类固醇。
