Mesh : Humans Aged Male Antineoplastic Combined Chemotherapy Protocols / therapeutic use Lymphoma, T-Cell / diagnosis pathology Doxorubicin / therapeutic use Vincristine / therapeutic use Intestinal Neoplasms / diagnosis pathology Cyclophosphamide / therapeutic use Prednisone / therapeutic use Colonoscopy

来  源:   DOI:10.1097/MD.0000000000038465   PDF(Pubmed)

Abstract:
BACKGROUND: Intestinal T-cell lymphomas are exceedingly rare diseases. Intestinal T-cell lymphoma NOS, as a \"wastebasket\" category, is difficult to diagnosis. Endoscopy can identify abnormal mucosa in most patients at a reasonably early stage. Therefore, it is crucial to increase the understanding of endoscopists in terms of the endoscopic characteristics of ITCL.
METHODS: A 74-year-old male alone with wasting as the major complaint, had multiple polypoid lesions in the large intestine. The patient then had endoscopic care.
METHODS: Only 1 polypoid lesion on white-light endoscopy in the sigmoid colon was pathologically diagnosed as intestinal T-cell lymphomas, not otherwise specified (ITCL-NOS).
METHODS: The patient underwent intensity-reduced CHOP therapy.
RESULTS: The patient is still with controlled disease but developed chemotherapy-related side effects.
CONCLUSIONS: In the individual with unexplained anemia and waste, endoscopy should not be delayed. For each of polypoid lesion on white-light endoscopy, the endoscopist need to remain cautious, because every lesion in the same patient can exhibit the independence of histopathological features. Meanwhile, we suggest that endoscopists should routinely observe the terminal ileum, even take biopsy samples if necessary.
摘要:
背景:肠道T细胞淋巴瘤是极为罕见的疾病。肠T细胞淋巴瘤NOS,作为“废纸屑篮”类别,很难诊断。内窥镜检查可以在合理的早期阶段识别大多数患者的异常粘膜。因此,提高内镜医师对ITCL内镜特征的认识至关重要.
方法:一名74岁男性,以消瘦为主要主诉,大肠有多个息肉样病变。然后患者接受了内窥镜护理。
方法:只有1例乙状结肠白光内镜息肉样病变病理诊断为肠道T细胞淋巴瘤,未指定(ITCL-NOS)。
方法:患者接受了强度降低的CHOP治疗。
结果:患者病情仍得到控制,但出现化疗相关副作用。
结论:在患有无法解释的贫血和废物的个体中,内窥镜检查不应延迟。对于白光内窥镜检查的每个息肉样病变,内窥镜医师需要保持谨慎,因为同一患者的每个病变都可以表现出组织病理学特征的独立性。同时,我们建议内镜医师应常规观察回肠末端,如果有必要,甚至取活检样本。
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