Abstract：
Cancer, a complicated and multi-dimensional medical concern worldwide, can be identified via either the growth of malignant tumours or colonisation of nearby tissues attributing to uncontrollable proliferation and division of cells promoted by several influential factors, including family history, exposure to pollutants, choice of lifestyle, and certain infections. The intricate processes underlying the development, expansion, and advancement of cancer are still being studied. However, there are a variety of therapeutic alternatives available for the diagnosis and treatment of cancer depending on the type and stage of cancer as well as the patient\'s individuality. The bioactive compoundsfortified nanofiber-based advanced therapies are revolutionary models for cancer detection and treatment, specifically targeting melanoma cells via exploring unique properties, such as increased surface area for payload, and imaging and bio-sensing capacities of nano-structured materials with minimal damage to functioning organs. The objective of the study was to gain knowledge regarding the potentiality of Nanofibers (NFs) fabricated using biomaterials in promoting cancer management along with providing a thorough overview of recent developmental initiatives, challenges, and future investigation strategies. Several fabrication approaches, such as electrospinning, self-assembly, phase separation, drawing, and centrifugal spinning of bio-compatible NFs along with characterization techniques, have been elaborated in the review.
摘要：
癌症,一个世界范围内复杂和多维的医学问题，可以通过恶性肿瘤的生长或附近组织的定植来鉴定，这归因于由几种影响因素促进的细胞的无法控制的增殖和分裂，包括家族史,暴露于污染物，生活方式的选择,某些感染。发展背后的复杂过程，扩展,癌症的进展仍在研究中。然而,根据癌症的类型和阶段以及患者的个性，有多种治疗方法可用于癌症的诊断和治疗。生物活性化合物强化纳米纤维为基础的先进疗法是癌症检测和治疗的革命性模型，通过探索独特的特性特异性靶向黑色素瘤细胞，例如增加有效载荷的表面积，以及纳米结构材料的成像和生物传感能力，对功能器官的损害最小。该研究的目的是获得有关使用生物材料制造的纳米纤维（NFs）在促进癌症管理方面的潜力的知识，并对最近的发展举措进行全面概述。挑战,以及未来的调查策略。几种制造方法，比如静电纺丝，自组装,相分离,绘图,生物相容性NFs的离心纺丝以及表征技术，已在审查中详细说明。
