PDF(Pubmed)
Abstract：
UNASSIGNED: Acute coronary syndrome (ACS) in young individuals (≤45 years) is increasingly recognized as a significant health concern, yet research in this demographic remains limited, particularly within the Palestinian context. This study aims to bridge this gap by comprehensively investigating the clinical characteristics, age-specific profiles, gender disparities, treatment modalities, and angiographic patterns of ACS in young patients compared to their older counterparts.
UNASSIGNED: A multi-centre observational study was conducted, enroling 468 participants aged 18-55 diagnosed with ACS and admitted to three prominent Palestinian hospitals. Data were collected from medical records, and statistical analysis was performed to assess demographic characteristics, clinical presentations, risk factors, treatment strategies, and outcomes.
UNASSIGNED: The majority of participants were male (87%), with a higher proportion in the older age group (>45 years). Clinical presentations varied, with non-ST segment elevation myocardial infarction (NSTEMI) being the most common diagnosis (48%). Risk factors such as smoking, hypertension, and diabetes were prevalent, with notable gender and age-specific differences. Percutaneous coronary intervention (PCI) was the predominant treatment strategy (83%), with consistent medication use across age groups.
UNASSIGNED: ACS in young patients poses a significant public health challenge in Palestine, necessitating tailored preventive strategies and comprehensive management approaches. Understanding the unique demographic and clinical characteristics of young ACS patients is crucial for informing targeted interventions and policies aimed at reducing the burden of cardiovascular disease in this population. These findings contribute valuable insights to the existing literature and underscore the importance of further research in this area to improve outcomes and mitigate the impact of ACS in young individuals globally.
UNASSIGNED: A multi-centre observational study was conducted, enroling 468 participants aged 18-55 diagnosed with ACS and admitted to three prominent Palestinian hospitals. Data were collected from medical records, and statistical analysis was performed to assess demographic characteristics, clinical presentations, risk factors, treatment strategies, and outcomes.
UNASSIGNED: The majority of participants were male (87%), with a higher proportion in the older age group (>45 years). Clinical presentations varied, with non-ST segment elevation myocardial infarction (NSTEMI) being the most common diagnosis (48%). Risk factors such as smoking, hypertension, and diabetes were prevalent, with notable gender and age-specific differences. Percutaneous coronary intervention (PCI) was the predominant treatment strategy (83%), with consistent medication use across age groups.
UNASSIGNED: ACS in young patients poses a significant public health challenge in Palestine, necessitating tailored preventive strategies and comprehensive management approaches. Understanding the unique demographic and clinical characteristics of young ACS patients is crucial for informing targeted interventions and policies aimed at reducing the burden of cardiovascular disease in this population. These findings contribute valuable insights to the existing literature and underscore the importance of further research in this area to improve outcomes and mitigate the impact of ACS in young individuals globally.
摘要：
■年轻个体（≤45岁）的急性冠状动脉综合征（ACS）越来越被认为是一种重要的健康问题。然而，对这一人口的研究仍然有限，特别是在巴勒斯坦的背景下。本研究旨在通过全面调查临床特征来弥合这一差距，特定年龄的配置文件，性别差异,治疗方式，年轻患者与老年患者相比的ACS血管造影模式。
■进行了多中心观察研究，招募了468名年龄在18-55岁之间的参与者，这些参与者被诊断出患有ACS，并入住了三家著名的巴勒斯坦医院。数据是从医疗记录中收集的，并进行统计分析以评估人口统计学特征，临床表现,危险因素，治疗策略,和结果。
■大多数参与者是男性（87％），在老年组（>45岁）中比例较高。临床表现各不相同，非ST段抬高型心肌梗死（NSTEMI）是最常见的诊断（48%）。吸烟等危险因素，高血压,糖尿病很普遍，具有明显的性别和年龄差异。经皮冠状动脉介入治疗（PCI）是主要的治疗策略（83％），各年龄组的药物使用一致。
■年轻患者中的ACS在巴勒斯坦构成了重大的公共卫生挑战，需要量身定制的预防战略和全面的管理方法。了解年轻ACS患者的独特人口统计学和临床特征对于提供旨在减轻该人群心血管疾病负担的针对性干预措施和政策至关重要。这些发现为现有文献提供了宝贵的见解，并强调了该领域进一步研究的重要性，以改善结果并减轻ACS对全球年轻人的影响。
■进行了多中心观察研究，招募了468名年龄在18-55岁之间的参与者，这些参与者被诊断出患有ACS，并入住了三家著名的巴勒斯坦医院。数据是从医疗记录中收集的，并进行统计分析以评估人口统计学特征，临床表现,危险因素，治疗策略,和结果。
■大多数参与者是男性（87％），在老年组（>45岁）中比例较高。临床表现各不相同，非ST段抬高型心肌梗死（NSTEMI）是最常见的诊断（48%）。吸烟等危险因素，高血压,糖尿病很普遍，具有明显的性别和年龄差异。经皮冠状动脉介入治疗（PCI）是主要的治疗策略（83％），各年龄组的药物使用一致。
■年轻患者中的ACS在巴勒斯坦构成了重大的公共卫生挑战，需要量身定制的预防战略和全面的管理方法。了解年轻ACS患者的独特人口统计学和临床特征对于提供旨在减轻该人群心血管疾病负担的针对性干预措施和政策至关重要。这些发现为现有文献提供了宝贵的见解，并强调了该领域进一步研究的重要性，以改善结果并减轻ACS对全球年轻人的影响。
