PDF(Pubmed)
Abstract：
UNASSIGNED: Vitamin D is a liposoluble steroid hormone that plays a crucial role in the maintenance of bone metabolism and calcium homoeostasis. Many studies on the effects of vitamin D on general health have been significantly increased, driven by new findings concerning the systemic and extraskeletal effects of this hormone. This study was performed to determine whether low levels of vitamin D were associated with hypertension in Syrian people.
UNASSIGNED: This retrospective cohort study consisted of 207 subjects, including 83 (40.1%) patients suffering from essential hypertension and 124 (59.9%) patients with normal blood pressure. Aged older than 18 years, who was referred to the endocrinology clinic from September 2022 to September 2023. The data were analysed by using SPSS (version 25). Logistic regression analyses were performed with adjustments for age, sex, and waist circumference.
UNASSIGNED: Hypertension rates were 73%, 20%, and 5% in 25-hydroxyvitamin D groups less than 12 ng/ml, 12-20 ng/mL, and greater than or equal to 20 ng/ml, respectively. Odds ratios (95% CIs) for hypertension adjusting for age, sex, and waist circumference were 178.6 (30.5_1045.6), 5.13 (0.9_26.5) for 25-hydroxyvitamin D levels less than 12 ng/ml, and 12-20 ng/ml, respectively, compared with the greater than or equal to 20 ng/ml group.
UNASSIGNED: This study has shown a high prevalence of low vitamin D levels (25OHVD/20 ng/ml) among a sample of Syrian people (78.3%). The lowest 25OHVD group was associated with a higher prevalence of hypertension, which refers to an adverse association between vitamin D level and essential hypertension. Further research is needed to confirm this relationship.
UNASSIGNED: This retrospective cohort study consisted of 207 subjects, including 83 (40.1%) patients suffering from essential hypertension and 124 (59.9%) patients with normal blood pressure. Aged older than 18 years, who was referred to the endocrinology clinic from September 2022 to September 2023. The data were analysed by using SPSS (version 25). Logistic regression analyses were performed with adjustments for age, sex, and waist circumference.
UNASSIGNED: Hypertension rates were 73%, 20%, and 5% in 25-hydroxyvitamin D groups less than 12 ng/ml, 12-20 ng/mL, and greater than or equal to 20 ng/ml, respectively. Odds ratios (95% CIs) for hypertension adjusting for age, sex, and waist circumference were 178.6 (30.5_1045.6), 5.13 (0.9_26.5) for 25-hydroxyvitamin D levels less than 12 ng/ml, and 12-20 ng/ml, respectively, compared with the greater than or equal to 20 ng/ml group.
UNASSIGNED: This study has shown a high prevalence of low vitamin D levels (25OHVD/20 ng/ml) among a sample of Syrian people (78.3%). The lowest 25OHVD group was associated with a higher prevalence of hypertension, which refers to an adverse association between vitamin D level and essential hypertension. Further research is needed to confirm this relationship.
摘要：
■维生素D是一种脂溶性类固醇激素，在维持骨代谢和钙稳态中起着至关重要的作用。许多关于维生素D对一般健康影响的研究已经显著增加，由有关该激素的全身和外作用的新发现驱动。这项研究是为了确定低水平的维生素D是否与叙利亚人民的高血压有关。
■这项回顾性队列研究由207名受试者组成，其中原发性高血压患者83例(40.1%),血压正常患者124例(59.9%)。年龄超过18岁,从2022年9月到2023年9月被转诊到内分泌学诊所。数据采用SPSS(第25版)进行分析。Logistic回归分析与年龄调整，性别,和腰围。
■高血压发生率为73%，20%,和5％的25-羟基维生素D组低于12纳克/毫升，12-20ng/mL，大于或等于20ng/ml，分别。高血压的赔率（95%CI）调整年龄，性别,腰围为178.6（30.5_1045.6），5.13（0.9_26.5）25-羟基维生素D水平低于12ng/ml，和12-20纳克/毫升，分别,大于或等于20ng/ml组。
■这项研究表明，在叙利亚人群样本中，低维生素D水平（25OHVD/20ng/ml）的患病率很高（78.3％）。25OHVD最低组高血压患病率较高，这是指维生素D水平与原发性高血压之间的不良关联。需要进一步的研究来证实这种关系。
■这项回顾性队列研究由207名受试者组成，其中原发性高血压患者83例(40.1%),血压正常患者124例(59.9%)。年龄超过18岁,从2022年9月到2023年9月被转诊到内分泌学诊所。数据采用SPSS(第25版)进行分析。Logistic回归分析与年龄调整，性别,和腰围。
■高血压发生率为73%，20%,和5％的25-羟基维生素D组低于12纳克/毫升，12-20ng/mL，大于或等于20ng/ml，分别。高血压的赔率（95%CI）调整年龄，性别,腰围为178.6（30.5_1045.6），5.13（0.9_26.5）25-羟基维生素D水平低于12ng/ml，和12-20纳克/毫升，分别,大于或等于20ng/ml组。
■这项研究表明，在叙利亚人群样本中，低维生素D水平（25OHVD/20ng/ml）的患病率很高（78.3％）。25OHVD最低组高血压患病率较高，这是指维生素D水平与原发性高血压之间的不良关联。需要进一步的研究来证实这种关系。
