关键词: burkitt lymphoma non-hodgkin lymphoma recurrence

来  源:   DOI:10.1097/MS9.0000000000002089   PDF(Pubmed)

Abstract:
UNASSIGNED: Burkitt lymphoma (BL) is an aggressive non-Hodgkin lymphoma characterized by chromosome 8 MYC gene translocation. It manifests in three clinical types: immunodeficiency-related, sporadic (nonendemic), and endemic (African), each differing in epidemiology and clinical behavior. Treatment typically involves enrollment in clinical trials or intensive chemotherapy regimens like R-CODOX-M/IVAC. The authors present a case of recurrent BL following treatment.
UNASSIGNED: A 13-year-old female presented with a gradually progressive swelling in the left parieto-occipital region. Examination revealed normal vital signs and a Glasgow coma scale, with seronegative findings on investigations. An excision of a subganglion soft tissue tumor was performed, revealing histopathological features suggestive of a small round blue cell tumor. After chemotherapy, the patient experienced a recurrence in the scalp region, diagnosed as BL.
UNASSIGNED: While scarce reports exist on BL in the scalp region, cases have been documented in various body locations. Treatment strategies, including chemotherapy and surgery, have shown promising results in managing the disease and improving symptoms.
UNASSIGNED: The recurrence of BL is rare, highlighting the importance of vigilance in monitoring patients post-treatment. The authors report a case of recurrent BL in a 13-year-old female, emphasizing the need for continued research and surveillance in managing this aggressive malignancy.
摘要:
伯基特淋巴瘤(BL)是一种侵袭性非霍奇金淋巴瘤,其特征是8号染色体MYC基因易位。它表现在三种临床类型:免疫缺陷相关,零星(非地方性),和地方性(非洲),流行病学和临床行为各有不同。治疗通常涉及临床试验或强化化疗方案如R-CODOX-M/IVAC的登记。作者介绍了一例治疗后复发的BL病例。
一名13岁女性患者出现左侧顶枕区逐渐进行性肿胀。检查显示生命体征正常,格拉斯哥昏迷评分,具有血清阴性调查结果。切除了神经节下软组织肿瘤,显示组织病理学特征,提示一个小的圆形蓝色细胞肿瘤。化疗后,患者头皮区域复发,诊断为BL。
虽然头皮区域的BL报告很少,已在各个身体位置记录了病例。治疗策略,包括化疗和手术,在控制疾病和改善症状方面显示出有希望的结果。
BL的复发是罕见的,强调在治疗后监测患者的警惕性的重要性。作者报告了一名13岁女性反复发作的BL病例,强调在管理这种侵袭性恶性肿瘤方面需要持续的研究和监测.
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