PDF(Pubmed)
Abstract：
Over the first years of life, the brain undergoes substantial organization in response to environmental stimulation. In a silent world, it may promote vision by (i) recruiting resources from the auditory cortex and (ii) making the visual cortex more efficient. It is unclear when such changes occur and how adaptive they are, questions that children with cochlear implants can help address. Here, we examined 7-18 years old children: 50 had cochlear implants, with delayed or age-appropriate language abilities, and 25 had typical hearing and language. High-density electroencephalography and functional near-infrared spectroscopy were used to evaluate cortical responses to a low-level visual task. Evidence for a \'weaker visual cortex response\' and \'less synchronized or less inhibitory activity of auditory association areas\' in the implanted children with language delays suggests that cross-modal reorganization can be maladaptive and does not necessarily strengthen the dominant visual sense.
摘要：
在生命的最初几年，大脑经历了大量的组织，以响应环境的刺激。在一个沉默的世界，它可以通过（i）从听觉皮层招募资源和（ii）使视觉皮层更有效来促进视力。目前还不清楚这种变化何时发生，以及它们的适应性如何，有人工耳蜗的儿童可以帮助解决的问题。这里,我们检查了7-18岁的儿童：50个有人工耳蜗，具有延迟或适合年龄的语言能力，25人具有典型的听力和语言。使用高密度脑电图和功能近红外光谱来评估皮层对低级视觉任务的反应。在有语言延迟的植入儿童中，“视觉皮层反应较弱”和“听觉联想区域的同步或抑制活动较少”的证据表明，跨模式重组可能是适应不良的，不一定会增强主导的视觉感觉。
