UNASSIGNED: A cross-sectional and exploratory study was conducted among pregnant women in the latent phase of labor, forming three study groups: normotensive or control (C, 38.8 ± 1.3 weeks of pregnancy, n = 22), preeclampsia with moderate features (P, 37.6 ± 1.4 weeks of pregnancy n = 10), and preeclampsia with severe features (SP, 36.9 ± 1.2 weeks of pregnancy, n = 12). None of the participants received anti-hypertensive treatment during their pregnancy. Linear and nonlinear features of beat-to-beat fHRV, including temporal, frequency, symbolic dynamics, and entropy measures, were analyzed to compare normotensive and preeclamptic groups.
UNASSIGNED: Significantly lower values of multiscale entropy (MSE) and short-term complexity index (Ci) were observed in the preeclamptic groups compared to the C group (p < 0.05). Additionally, higher values of SDNN (standard deviation of R-R intervals) and higher values of low-frequency power (LF) were found in the P group compared to the C group.
UNASSIGNED: Our findings indicate that changes in the complexity of fetal heart rate fluctuations may indicate possible disruptions in the autonomic nervous system of fetuses in groups affected by undiagnosed preeclampsia during pregnancy. Reduced complexity and shifts in fetal autonomic cardiac activity could be associated with preeclampsia\'s pathophysiological mechanisms during the latent phase of labor.
■对处于分娩潜伏期的孕妇进行了一项横断面和探索性研究,形成三个研究组:血压正常或对照(C,妊娠38.8±1.3周,n=22),具有中度特征的先兆子痫(P,怀孕37.6±1.4周n=10),和具有严重特征的先兆子痫(SP,妊娠36.9±1.2周,n=12)。没有参与者在怀孕期间接受抗高血压治疗。逐拍fHRV的线性和非线性特征,包括时间,频率,符号动力学,和熵度量,进行分析,比较血压正常和先兆子痫组。
■与C组相比,在先兆子痫组中观察到多尺度熵(MSE)和短期复杂性指数(Ci)的值明显较低(p<0.05)。此外,与C组相比,P组的SDNN值(R-R间期的标准偏差)和低频功率(LF)值较高.
■我们的研究结果表明,胎儿心率波动的复杂性变化可能表明在怀孕期间受未诊断先兆子痫影响的人群中,胎儿自主神经系统可能受到破坏。胎儿自主性心脏活动的复杂性降低和变化可能与先兆子痫潜伏期的病理生理机制有关。