UNASSIGNED: Ovid MEDLINE (1946-2023), Embase.com (1947-2023), and Web of Science (All Databases 1900-2023).
UNASSIGNED: Inclusion criteria were the use of IOUS for the management of oral tongue cancer. Studies that did not report quantitative data were excluded. Additionally, studies that were not contributory to meta-analysis, or a narrative analysis of pooled results were excluded. Selection was carried out by 2 reviewers. A total of 2417 studies were initially identified, with 12 ultimately being included in this review, and 7 included in the meta-analysis. Data were extracted by 2 investigators and were pooled using a random-effects model.
UNASSIGNED: Our meta-analysis reveals a pooled correlation coefficient of 0.92 (95% confidence interval: 0.80-0.96) for studies comparing uTT to hTT. Studies comparing IOUS-assisted resection to conventional resection found IOUS-assisted resection yielded wider nearest margins in all studies reporting this outcome.
UNASSIGNED: IOUS reliably measures TT, similarly to that of histopathology measurement. IOUS-assisted resection, which allows the surgeon to view the deep extent of tumor invasion, may increase closest radial margin distance compared to conventional resection. IOUS-assisted resection may represent a more reliable approach to achieving clear margins than conventional resection.
■OvidMEDLINE(1946-2023),Embase.com(1947-2023),和WebofScience(所有数据库1900-2023)。
■纳入标准是使用IOUS治疗口腔舌癌。未报告定量数据的研究被排除在外。此外,对荟萃分析没有贡献的研究,或排除对合并结果的叙述性分析.由2名评审员进行选择。最初总共确定了2417项研究,最终有12人被纳入本次审查,和7纳入荟萃分析。数据由2名研究人员提取,并使用随机效应模型进行汇总。
■我们的荟萃分析显示,将uTT与hTT进行比较的研究的合并相关系数为0.92(95%置信区间:0.80-0.96)。比较IOUS辅助切除与常规切除的研究发现,在所有报告此结果的研究中,IOUS辅助切除产生了更宽的最近边缘。
■IOUS可靠地测量TT,类似于组织病理学测量。IOUS辅助切除,这使得外科医生能够观察到肿瘤浸润的深度,与常规切除相比,可能会增加最接近的径向边缘距离。IOUS辅助切除可能是比常规切除更可靠的获得清晰边缘的方法。