PDF(Pubmed)
Abstract：
Spontaneous thrombosis of an unruptured large or giant saccular intracranial aneurysm is a well-known phenomenon and can cause ischemic stroke (IS), which is a rare event. The possible pathogenic mechanisms of IS include distal embolic occlusion secondary to migration of the intra-aneurysmal thrombus, occlusion of the parent artery lumen caused by the retrograde extension of the aneurysmal thrombosis, external compression of the parent artery due to the increased aneurysmal mass effect. Among these, IS due to simultaneous thromboses of the aneurysm and its parent artery is extremely rare, with only a few cases reported in the literature. Herein, we present a case of a 18-year-old woman who suffered an acute IS, attribute to spontaneous complete thrombosis of an unruptured large saccular aneurysm of the right middle cerebral artery with occlusion of the parent artery, and we review the literature simultaneously.
摘要：
未破裂的大型或巨大囊状颅内动脉瘤的自发性血栓形成是众所周知的现象，可导致缺血性卒中（IS）。这是一个罕见的事件。IS的可能致病机制包括继发于动脉瘤内血栓迁移的远端栓塞闭塞，由动脉瘤血栓形成的逆行延伸引起的父动脉腔闭塞，由于增加的动脉瘤质量效应，对父动脉的外部压缩。其中,由于动脉瘤和其父动脉的同时血栓形成是非常罕见的，文献中只有少数病例报道。在这里，我们介绍了一个18岁女性患有急性IS的病例，归因于右大脑中动脉未破裂的大囊状动脉瘤伴父动脉闭塞的自发性完全血栓形成，我们同时回顾了文献。
