METHODS: Prospective multicenter ancillary study using data from the RECRET study. Nulliparous women, with no reported history, with second- and third-trimester ultrasound examinations performed by the same ultrasonographer and using the same ultrasound machine were recruited. The global score and the individual score of each ultrasound image were compared between second- and third-trimester ultrasound scan. The sample size was calculated for a non-inferiority (one-sided) paired Student t test.
RESULTS: 103 women with 1606 anonymized ultrasound images were included. The median term at second- and third-trimester ultrasound scan was 22.2 weeks gestation (22.0-22.7) and 31.6 weeks gestation (30.7-34.7), respectively. The mean global score of ultrasound images was comparable between the second- and the third-trimester ultrasound examination (32.37 ± 2.62 versus 31.80 ± 3.27, p = 0.13). Means scores for each biometric parameters i.e. head circumference, abdominal circumference, and femur diaphysis length were comparable. The scores for the four-chamber view (5.11 ± 0.91 versus 5.36 ± 0.75, p = 0.02) and the spine (4.18 ± 1.17 versus 5.22 ± 1.02, p < 0.001) were significantly lower in the third trimester compared to the second trimester. The score for the kidney image was significantly higher for third trimester images compared to second trimester images (4.73 ± 0.51 versus 4.32 ± 0.67, p < 0.001.
CONCLUSIONS: Biometrics parameters quality scores images previously validated for the second trimester ultrasound scan can be also used for the third trimester scan. However, anatomical quality scores images performances may vary between the second and the third trimester scan.
方法:使用RECRET研究数据进行前瞻性多中心辅助研究。未产妇女,没有历史报道,我们招募了由同一超声医师和使用同一超声机器进行的孕中期和晚期超声检查。比较孕中期和晚期超声扫描中各超声图像的整体评分和个体评分。对于非劣效性(单侧)配对Studentt检验计算样本量。
结果:包括103名具有1606个匿名超声图像的女性。妊娠中期和中期超声扫描的中位足月为妊娠22.2周(22.0-22.7)和妊娠31.6周(30.7-34.7),分别。在妊娠中期和妊娠中期超声检查中,超声图像的平均全局得分相当(32.37±2.62对31.80±3.27,p=0.13)。每个生物特征参数的平均分数,即头围,腹围,和股骨骨干长度相当。与妊娠中期相比,妊娠中期四腔视图(5.11±0.91对5.36±0.75,p=0.02)和脊柱(4.18±1.17对5.22±1.02,p<0.001)的得分显着降低。与妊娠中期图像相比,妊娠中期图像的肾脏图像得分明显更高(4.73±0.51对4.32±0.67,p<0.001。
结论:生物特征参数质量评分图像先前验证的孕中期超声扫描也可用于孕中期扫描。然而,解剖质量评分图像性能可能会有所不同之间的第二和第三个三个月的扫描。