Abstract：
BACKGROUND: Neurosurgical interventions and trauma are common causes of damage to the optic nerve. This determines the relevance of research for solutions aimed at restoration of the nerve\'s anatomical integrity, electrical conductivity, and subsequently - restoration of its function. Restore a damaged (cut) optic nerve using n. suralis autograft in vivo.
METHODS: The experiment involved reconstruction of the optic nerve through injury modulation, graft placement and restored nerve harvest and evaluation. Injury modulation included removal of a fragment of the optic nerve. Autograft harvesting and placement involved resection of a fragment of the sural (sensory) nerve and its subsequent anastomosis in place of the removed fragment of the optic nerve. As an experimental model, a rabbit of the \"Burgundy\" breed was used. The animal was previously examined for the presence of infectious and other diseases to confirm its health.
RESULTS: Four months post operatively when stimulating the operated right eye, low-amplitude components altered in shape are registered. Thus, signs of mild restoration of electrical conductivity on the treated optic nerve were seen.
CONCLUSIONS: Our initial experience shows the technical feasibility of reconstructing the optic nerve using an autograft, the possibility of axonal growth through the graft and, in the future, using this method for direct optic nerve reconstruction, as well as a bypass method for damage to the optic nerve with various tumor diseases of the optic nerve, tumors of the chiasmatic-sellar localization, orbital injuries.
METHODS: The experiment involved reconstruction of the optic nerve through injury modulation, graft placement and restored nerve harvest and evaluation. Injury modulation included removal of a fragment of the optic nerve. Autograft harvesting and placement involved resection of a fragment of the sural (sensory) nerve and its subsequent anastomosis in place of the removed fragment of the optic nerve. As an experimental model, a rabbit of the \"Burgundy\" breed was used. The animal was previously examined for the presence of infectious and other diseases to confirm its health.
RESULTS: Four months post operatively when stimulating the operated right eye, low-amplitude components altered in shape are registered. Thus, signs of mild restoration of electrical conductivity on the treated optic nerve were seen.
CONCLUSIONS: Our initial experience shows the technical feasibility of reconstructing the optic nerve using an autograft, the possibility of axonal growth through the graft and, in the future, using this method for direct optic nerve reconstruction, as well as a bypass method for damage to the optic nerve with various tumor diseases of the optic nerve, tumors of the chiasmatic-sellar localization, orbital injuries.
摘要：
背景：神经外科介入和创伤是视神经损伤的常见原因。这决定了旨在恢复神经解剖完整性的解决方案的研究的相关性，电导率，随后-恢复其功能。
目的：使用自体腓肠修复受损（切断）的视神经。
方法：实验涉及通过损伤调制重建视神经，移植和恢复神经收获和评估。损伤调节包括去除视神经碎片。自体移植物的收获和放置涉及切除腓肠（感觉）神经的碎片，并随后进行吻合以代替切除的视神经碎片。作为一个实验模型，使用了“勃艮第”品种的兔子。该动物先前曾接受过传染病和其他疾病的检查，以确认其健康状况。
结果：术后4个月刺激手术后的右眼，形状改变的低振幅分量被记录。因此，在治疗的视神经上看到电导率轻度恢复的迹象。
结论：我们的初步经验表明，使用自体移植重建视神经的技术可行性，通过移植物轴突生长的可能性，在未来,用这种方法直接重建视神经，以及各种视神经肿瘤疾病对视神经损伤的旁路方法，交叉鞍区定位的肿瘤，眼眶损伤。
目的：使用自体腓肠修复受损（切断）的视神经。
方法：实验涉及通过损伤调制重建视神经，移植和恢复神经收获和评估。损伤调节包括去除视神经碎片。自体移植物的收获和放置涉及切除腓肠（感觉）神经的碎片，并随后进行吻合以代替切除的视神经碎片。作为一个实验模型，使用了“勃艮第”品种的兔子。该动物先前曾接受过传染病和其他疾病的检查，以确认其健康状况。
结果：术后4个月刺激手术后的右眼，形状改变的低振幅分量被记录。因此，在治疗的视神经上看到电导率轻度恢复的迹象。
结论：我们的初步经验表明，使用自体移植重建视神经的技术可行性，通过移植物轴突生长的可能性，在未来,用这种方法直接重建视神经，以及各种视神经肿瘤疾病对视神经损伤的旁路方法，交叉鞍区定位的肿瘤，眼眶损伤。
