Abstract：
The pharmaceutical and nutraceutical potentials of whole fruit, pulp and seeds of Rosa pimpinellifolia L. were evaluated. Forty-two phenolic compounds and two triterpenoids were identified in extracts by LC-MS/MS and GC-MS, respectively. The most prominent compounds were ellagic acid, catechin, epicatechin, tannic acid, quercetin, oleanolic acid, and ursolic acid. The highest enzyme inhibitory activities of the extracts (94.83%) were obtained against angiotensin-converting enzyme and were almost equal to those of the commercial standard (lisinopril, 98.99%). Whole fruit and pulp extracts (IC50:2.47 and 1.52 μg DW/mL) exhibited higher antioxidant capacity than the standards (α-tocopherol, IC50:9.89 μg DW/mL). The highest antibacterial activity was obtained against Bacillus cereus (MIC: 256 μg/mL) for the whole fruit extract. Correlation analyses were conducted to find the correlation between individual phenolics and enzyme inhibitory activities. The results showed the remarkable future of not only the edible part but also the seeds of black rose hips in phytochemical and functional aspects.
摘要：
整个水果的药物和营养潜力，对刺梨的果肉和种子进行了评价。通过LC-MS/MS和GC-MS鉴定了提取物中的42种酚类化合物和两种三萜类化合物，分别。最突出的化合物是鞣花酸,儿茶素,表儿茶素,鞣酸,槲皮素,齐墩果酸，和熊果酸。提取物对血管紧张素转换酶的酶抑制活性最高（94.83％），几乎与商业标准品（赖诺普利，98.99%）。全果和果肉提取物（IC50：2.47和1.52μgDW/mL）表现出比标准更高的抗氧化能力（α-生育酚，IC50:9.89μgDW/mL)。全果实提取物对蜡样芽孢杆菌的抗菌活性最高(MIC:256μg/mL)。进行相关分析以发现单个酚类物质与酶抑制活性之间的相关性。结果表明，不仅在植物化学和功能方面，黑玫瑰的可食用部分和种子也具有显着的前景。
