PDF(Pubmed)
Abstract：
Orthodontic treatments, while essential for achieving optimal oral health, present challenges in infection control due to the propensity for bacterial adhesion and biofilm formation on orthodontic appliances. Silver-coated orthodontic materials have emerged as a promising solution, leveraging the potent antimicrobial properties of silver nanoparticles (AgNPs). Antibacterial coatings are used in orthodontics to prevent the formation of bacterial biofilms. This systematic review evaluated the literature on antimicrobial silver coatings on fixed orthodontic appliances, including archwires, brackets, and microimplants. Two evaluators, working independently, rigorously conducted a comprehensive search of various databases, including PubMed, PubMed Central, Embase, Scopus and Web of Science. This systematic review comprehensively examined in vitro studies investigating the antimicrobial efficacy of silver-coated orthodontic archwires, brackets, and microimplants. The review registered in PROSPERO CRD42024509189 synthesized findings from 18 diverse studies, revealing consistent and significant reductions in bacterial adhesion, biofilm formation, and colony counts with the incorporation of AgNPs. Key studies demonstrated the effectiveness of silver-coated archwires and brackets against common oral bacteria, such as Streptococcus mutans and Staphylococcus aureus. Microimplants coated with AgNPs also exhibited notable antimicrobial activity against a range of microorganisms. The systematic review revealed potential mechanisms underlying these antimicrobial effects, highlighted implications for infection prevention in orthodontic practice, and suggested future research avenues. Despite some study heterogeneity and limitations, the collective evidence supports the potential of silver-coated orthodontic materials in mitigating bacterial complications, emphasizing their relevance in advancing infection control measures in orthodontics.
摘要：
正畸治疗,虽然对于实现最佳口腔健康至关重要，由于正畸矫治器上细菌粘附和生物膜形成的倾向，在感染控制方面面临挑战。镀银正畸材料已经成为一种有前途的解决方案，利用银纳米颗粒(AgNPs)的有效抗菌性能。在正畸中使用抗菌涂层来防止细菌生物膜的形成。这篇系统的综述评估了固定正畸矫治器上抗菌银涂层的文献，包括弓丝，括号,和微植入物。两名评估人员,独立工作,严格对各种数据库进行全面搜索，包括PubMed,PubMedCentral,Embase,Scopus和WebofScience本系统综述全面检查了体外研究，研究了镀银正畸弓丝的抗菌功效，括号,和微植入物。PROSPEROCRD42024509189中注册的评论综合了18项不同研究的结果，揭示细菌粘附的一致和显著减少，生物膜的形成，和菌落计数与AgNP的掺入。关键研究证明了银涂层弓丝和托槽对常见口腔细菌的有效性，如变形链球菌和金黄色葡萄球菌。涂覆有AgNP的微植入物还表现出对一系列微生物的显著抗微生物活性。系统评价揭示了这些抗菌作用的潜在机制，强调了正畸实践中预防感染的意义，并提出了未来的研究途径。尽管有一些研究的异质性和局限性，集体证据支持镀银正畸材料在减轻细菌并发症方面的潜力，强调它们在推进正畸感染控制措施中的相关性。
