PDF(Pubmed)
Abstract：
Immunoglobulin G4 (IgG4)-related disease has the potential to impact any part of the body, including the walls of large- and medium-sized blood vessels and the ureters. While histopathologic examination is currently the standard method for identifying organ involvement and diagnosing IgG4-related disease (IgG4-RD), obtaining biopsy or surgical samples from vessel or ureteral walls is challenging. Given that patients may display only mild symptoms, non-invasive imaging plays a vital role in both diagnosing and managing IgG4-related diseases. Multidetector CT scans are valuable in establishing the primary diagnosis, identifying anatomical landmarks and assessing their relationships. Involvement of the genitourinary organs, such as the ureter, bladder, urethra, and male and female reproductive organs in IgG4-RD, is infrequent when compared to kidney involvement. The imaging findings may include the presence of a localised mass within or surrounding the affected organ or a generalised enlargement of the organ. This report includes cross-sectional images of five cases of IgG4-RD involving large- and medium-sized blood vessels (the aorta and superior mesenteric artery) and the ureters.
UNASSIGNED: This case series provides insight into the various imaging appearances of IgG4-related retroperitoneal organ involvement and helps differentiate it radiologically from retroperitoneal fibrosis.
UNASSIGNED: This case series provides insight into the various imaging appearances of IgG4-related retroperitoneal organ involvement and helps differentiate it radiologically from retroperitoneal fibrosis.
摘要：
免疫球蛋白G4（IgG4）相关疾病有可能影响身体的任何部位，包括大中型血管壁和输尿管。虽然组织病理学检查目前是鉴定器官受累和诊断IgG4相关疾病（IgG4-RD）的标准方法，从血管或输尿管壁获取活检或手术样本具有挑战性。鉴于患者可能只表现出轻微的症状，非侵入性成像在IgG4相关疾病的诊断和治疗中发挥着至关重要的作用.多探测器CT扫描在建立初步诊断方面很有价值，识别解剖标志并评估它们的关系。泌尿生殖器官的参与，比如输尿管，膀胱,尿道,以及IgG4-RD中的男性和女性生殖器官，与肾脏受累相比是罕见的。成像发现可以包括受影响的器官内或周围的局部肿块的存在或器官的普遍扩大。本报告包括5例IgG4-RD的横截面图像，涉及大，中型血管（主动脉和肠系膜上动脉）和输尿管。
■本病例系列提供了对IgG4相关腹膜后器官受累的各种影像学表现的见解，并有助于在放射学上将其与腹膜后纤维化区分开。
■本病例系列提供了对IgG4相关腹膜后器官受累的各种影像学表现的见解，并有助于在放射学上将其与腹膜后纤维化区分开。
