PDF(Pubmed)
Abstract：
UNASSIGNED: Diabetic foot ulcers (DFUs) are serious complications that induce a high risk of lower extremity amputations and mortality. Compared with the standard of care, few reports analyzed the outcome of surgical treatment mainly for diabetic toe deformities and ulcers. The aim of this study is to collate evidence on the outcomes of interphalangeal resection arthroplasty (IP-RA) in preventing and treating diabetic toe ulcers distal to the metatarsophalangeal joint.
UNASSIGNED: A search strategy has been developed including electronic databases from inception. Only ulcers distal to the metatarsophalangeal joints were included. Noninfected and infected ulcers were also included at any toe location (dorsal/side/plantar). Outcomes were defined as healing rate, time to heal, ulcer recurrence, ulcer transfer, postintervention infection, wound dehiscence, and additional surgeries including amputation. Proportional meta-analysis was conducted for frequency outcomes.
UNASSIGNED: Six observational studies comprising 217 patients with 244 IP-RA procedures were included. The mean follow-up period was 23.4 ± 8.2 months. Weighted frequencies were as follows: healing rate (93.6%), ulcer recurrence frequency (4.3%), ulcer transfer frequency (15.4%), postoperative infection (10.5%), wound dehiscence (17.8%), revision surgery (5%), and amputation rate (3.4%). The mean healing time was 4.3 ± 1.8 weeks.
UNASSIGNED: This review suggests that IP-RA is effective in preventing and treating diabetic toe deformities and ulcers with a modest rate of complications for this specific and often challenging clinical presentation.
UNASSIGNED: A search strategy has been developed including electronic databases from inception. Only ulcers distal to the metatarsophalangeal joints were included. Noninfected and infected ulcers were also included at any toe location (dorsal/side/plantar). Outcomes were defined as healing rate, time to heal, ulcer recurrence, ulcer transfer, postintervention infection, wound dehiscence, and additional surgeries including amputation. Proportional meta-analysis was conducted for frequency outcomes.
UNASSIGNED: Six observational studies comprising 217 patients with 244 IP-RA procedures were included. The mean follow-up period was 23.4 ± 8.2 months. Weighted frequencies were as follows: healing rate (93.6%), ulcer recurrence frequency (4.3%), ulcer transfer frequency (15.4%), postoperative infection (10.5%), wound dehiscence (17.8%), revision surgery (5%), and amputation rate (3.4%). The mean healing time was 4.3 ± 1.8 weeks.
UNASSIGNED: This review suggests that IP-RA is effective in preventing and treating diabetic toe deformities and ulcers with a modest rate of complications for this specific and often challenging clinical presentation.
摘要：
■糖尿病足溃疡（DFU）是严重的并发症，会导致下肢截肢和死亡的高风险。与护理标准相比，很少有报道分析手术治疗的结果，主要是糖尿病脚趾畸形和溃疡。这项研究的目的是整理指间切除术（IP-RA）在预防和治疗meta趾关节远端糖尿病性脚趾溃疡方面的结果的证据。
■从一开始就开发了包括电子数据库的搜索策略。仅包括meta趾关节远端溃疡。未感染和感染的溃疡也包括在任何脚趾位置(背侧/侧/足底)。结果定义为治愈率，时间愈合，溃疡复发，溃疡转移，干预后感染，伤口裂开,和额外的手术，包括截肢。对频率结果进行比例荟萃分析。
■纳入了6项观察性研究，包括217例244例IP-RA手术患者。平均随访时间为23.4±8.2个月。加权频率如下：治愈率（93.6％），溃疡复发频率（4.3%），溃疡转移频率（15.4%），术后感染（10.5%），伤口裂开（17.8%），翻修手术（5%），和截肢率(3.4%)。平均愈合时间为4.3±1.8周。
■这篇综述表明，IP-RA在预防和治疗糖尿病性脚趾畸形和溃疡方面是有效的，对于这种特殊且通常具有挑战性的临床表现，其并发症发生率适中。
■从一开始就开发了包括电子数据库的搜索策略。仅包括meta趾关节远端溃疡。未感染和感染的溃疡也包括在任何脚趾位置(背侧/侧/足底)。结果定义为治愈率，时间愈合，溃疡复发，溃疡转移，干预后感染，伤口裂开,和额外的手术，包括截肢。对频率结果进行比例荟萃分析。
■纳入了6项观察性研究，包括217例244例IP-RA手术患者。平均随访时间为23.4±8.2个月。加权频率如下：治愈率（93.6％），溃疡复发频率（4.3%），溃疡转移频率（15.4%），术后感染（10.5%），伤口裂开（17.8%），翻修手术（5%），和截肢率(3.4%)。平均愈合时间为4.3±1.8周。
■这篇综述表明，IP-RA在预防和治疗糖尿病性脚趾畸形和溃疡方面是有效的，对于这种特殊且通常具有挑战性的临床表现，其并发症发生率适中。
