PDF(Pubmed)
Abstract：
UNASSIGNED: To assess the prevalence and risk factors for chronic kidney disease (CKD) among adults with type 2 diabetes within primary care.
UNASSIGNED: This cross-sectional study evaluated 1319 individuals receiving standard care across 26 primary units from July 2017 to January 2023. The estimated glomerular filtration rate (eGFR) and albuminuria were used for the diagnosis of CKD. CKD was defined by eGFR values of <60 mL/min/1.73 m2 and/or albumin-to-creatine ratio ≥30 mg/g. Logistic regression was applied to identify factors associated with CKD and study variables.
UNASSIGNED: The median age of participants (60.6% females) was 55 years and the median diabetes duration was 10 years. The overall CKD prevalence in the study population was 39.2%. Within the CKD group, the prevalence rates of albuminuria, albuminuria coupled with low eGFR and isolated low eGFR were 72.1%, 19%, and 8.9%, respectively. The prevalence of CKD was 30.6% among participants under 40 years old and a higher value was observed in middle-aged adults with early-onset diabetes (at age <40 years) compared with the later-onset group. Multivariable analyses identified associations between CKD and factors such as age, the male sex, diabetes duration, hypertension, retinopathy, and metformin use.
UNASSIGNED: A relatively high prevalence of CKD, especially in non-elderly adults, was revealed in this primary care study. Early recognition strategies for CKD are crucial for timely prevention within primary care.
UNASSIGNED: This cross-sectional study evaluated 1319 individuals receiving standard care across 26 primary units from July 2017 to January 2023. The estimated glomerular filtration rate (eGFR) and albuminuria were used for the diagnosis of CKD. CKD was defined by eGFR values of <60 mL/min/1.73 m2 and/or albumin-to-creatine ratio ≥30 mg/g. Logistic regression was applied to identify factors associated with CKD and study variables.
UNASSIGNED: The median age of participants (60.6% females) was 55 years and the median diabetes duration was 10 years. The overall CKD prevalence in the study population was 39.2%. Within the CKD group, the prevalence rates of albuminuria, albuminuria coupled with low eGFR and isolated low eGFR were 72.1%, 19%, and 8.9%, respectively. The prevalence of CKD was 30.6% among participants under 40 years old and a higher value was observed in middle-aged adults with early-onset diabetes (at age <40 years) compared with the later-onset group. Multivariable analyses identified associations between CKD and factors such as age, the male sex, diabetes duration, hypertension, retinopathy, and metformin use.
UNASSIGNED: A relatively high prevalence of CKD, especially in non-elderly adults, was revealed in this primary care study. Early recognition strategies for CKD are crucial for timely prevention within primary care.
摘要：
■评估初级保健范围内成人2型糖尿病患者慢性肾病（CKD）的患病率和危险因素。
■这项横断面研究评估了2017年7月至2023年1月在26个主要单位中接受标准护理的1319人。估计的肾小球滤过率（eGFR）和蛋白尿用于诊断CKD。CKD定义为eGFR值<60mL/min/1.73m2和/或白蛋白与肌酸之比≥30mg/g。Logistic回归用于确定与CKD和研究变量相关的因素。
参与者的中位年龄（60.6%为女性）为55岁，中位糖尿病病程为10年。研究人群中CKD的总体患病率为39.2%。在CKD组中，白蛋白尿的患病率，白蛋白尿加上低eGFR和孤立的低eGFR为72.1%，19%,和8.9%，分别。在40岁以下的参与者中，CKD的患病率为30.6％，与晚发病组相比，早发性糖尿病（年龄<40岁）的中年人的CKD患病率更高。多变量分析确定了CKD与年龄、男性,糖尿病持续时间，高血压,视网膜病变,和二甲双胍的使用。
■CKD患病率相对较高，尤其是在非老年人中，在这项初级保健研究中揭示了。CKD的早期识别策略对于初级保健中的及时预防至关重要。
■这项横断面研究评估了2017年7月至2023年1月在26个主要单位中接受标准护理的1319人。估计的肾小球滤过率（eGFR）和蛋白尿用于诊断CKD。CKD定义为eGFR值<60mL/min/1.73m2和/或白蛋白与肌酸之比≥30mg/g。Logistic回归用于确定与CKD和研究变量相关的因素。
参与者的中位年龄（60.6%为女性）为55岁，中位糖尿病病程为10年。研究人群中CKD的总体患病率为39.2%。在CKD组中，白蛋白尿的患病率，白蛋白尿加上低eGFR和孤立的低eGFR为72.1%，19%,和8.9%，分别。在40岁以下的参与者中，CKD的患病率为30.6％，与晚发病组相比，早发性糖尿病（年龄<40岁）的中年人的CKD患病率更高。多变量分析确定了CKD与年龄、男性,糖尿病持续时间，高血压,视网膜病变,和二甲双胍的使用。
■CKD患病率相对较高，尤其是在非老年人中，在这项初级保健研究中揭示了。CKD的早期识别策略对于初级保健中的及时预防至关重要。
