PDF(Pubmed)
Abstract：
BACKGROUND: Synthetic cannabinoid receptor agonists (SCRAs) are associated with significant toxicity and are increasingly used in electronic vaping devices. We assessed the availability of SCRA vaping products to UK purchasers on the surface web.
METHODS: An internet snapshot survey was performed between October 2022 and January 2023 on \'google.com\' using the search terms \"buy c-liquid vape\", \"buy herbal incense vape liquid\", \"buy cannabis vape liquid\", \"buy hashish vape liquid\", \"buy K2 vape liquid\".
RESULTS: 62 websites selling 128 SCRA vaping brands were identified. Most were purportedly based in the USA (41 websites, 66%) and most sold other controlled substances. Purchase incentives offered included discreet packaging (38, 61%), discounts for bulk purchase (34, 55%) and tracked delivery (30, 48%). Many websites stated SCRA products were: not for human consumption (41, 66%), for research purposes only (15, 24%), or legal (28, 45%). Websites sold a median (IQR) of 16 (7-25) SCRA vaping brands. Almost all were bottles of vaping liquid (1220/1225, 99.6%). The most common bottle size was 5mL (60%), the median (IQR) total volume of SCRA liquid per sale was 50mL (10-200mL). Median (IQR) price was £3.39/mL (£2.01/mL- £5.29/mL). Price decreased with increasing volume purchased (£6.58/mL for ≤ 5mL, £1.60/mL for > 200mL).
CONCLUSIONS: SCRA vaping products are easily obtainable online, in both small and bulk quantities. Information provided to purchasers on safety and legality is lacking or misleading. Further studies are needed to confirm the chemistry of these products. Policymakers should consider steps to limit the potential harm caused by the purchase and use of these products.
METHODS: An internet snapshot survey was performed between October 2022 and January 2023 on \'google.com\' using the search terms \"buy c-liquid vape\", \"buy herbal incense vape liquid\", \"buy cannabis vape liquid\", \"buy hashish vape liquid\", \"buy K2 vape liquid\".
RESULTS: 62 websites selling 128 SCRA vaping brands were identified. Most were purportedly based in the USA (41 websites, 66%) and most sold other controlled substances. Purchase incentives offered included discreet packaging (38, 61%), discounts for bulk purchase (34, 55%) and tracked delivery (30, 48%). Many websites stated SCRA products were: not for human consumption (41, 66%), for research purposes only (15, 24%), or legal (28, 45%). Websites sold a median (IQR) of 16 (7-25) SCRA vaping brands. Almost all were bottles of vaping liquid (1220/1225, 99.6%). The most common bottle size was 5mL (60%), the median (IQR) total volume of SCRA liquid per sale was 50mL (10-200mL). Median (IQR) price was £3.39/mL (£2.01/mL- £5.29/mL). Price decreased with increasing volume purchased (£6.58/mL for ≤ 5mL, £1.60/mL for > 200mL).
CONCLUSIONS: SCRA vaping products are easily obtainable online, in both small and bulk quantities. Information provided to purchasers on safety and legality is lacking or misleading. Further studies are needed to confirm the chemistry of these products. Policymakers should consider steps to limit the potential harm caused by the purchase and use of these products.
摘要：
背景：合成大麻素受体激动剂（SCRA）与显着的毒性相关，并且越来越多地用于电子烟装置中。我们评估了表面网络上英国购买者的SCRA电子烟产品的可用性。
方法：在2022年10月至2023年1月期间，在“google.com”上使用搜索词“购买c-liquidvape”进行了互联网快照调查，\“购买草药香vape液体\”，\“购买大麻vape液体\”，\“购买大麻vape液体\”，“购买K2vape液体”。
结果：确定了62个销售128个SCRAvaping品牌的网站。大多数据称位于美国(41个网站，66%)，大多数出售其他受控物质。提供的购买激励措施包括谨慎的包装(38%，61%)，批量购买（34，55%）和跟踪交付（30，48%）的折扣。许多网站表示SCRA产品是：不供人类消费（41，66％），仅用于研究目的(15%，24%)，或合法（28，45%）。网站销售的中位数（IQR）为16（7-25）SCRAvaping品牌。几乎所有的瓶子都是vaping液体（1220/1225，99.6％）。最常见的瓶子尺寸为5mL（60％），每次销售的SCRA液体的中位数（IQR）总体积为50mL（10-200mL）。中位数（IQR）价格为3.39英镑/mL（2.01英镑/mL-5.29英镑/mL）。价格随着购买量的增加而下降(≤5mL，6.58英镑/mL，>200mL的1.60英镑/mL）。
结论：SCRAvaping产品很容易在线获得，小批量和散装。向购买者提供的有关安全性和合法性的信息缺乏或具有误导性。需要进一步的研究来证实这些产品的化学性质。政策制定者应考虑采取步骤限制购买和使用这些产品所造成的潜在危害。
方法：在2022年10月至2023年1月期间，在“google.com”上使用搜索词“购买c-liquidvape”进行了互联网快照调查，\“购买草药香vape液体\”，\“购买大麻vape液体\”，\“购买大麻vape液体\”，“购买K2vape液体”。
结果：确定了62个销售128个SCRAvaping品牌的网站。大多数据称位于美国(41个网站，66%)，大多数出售其他受控物质。提供的购买激励措施包括谨慎的包装(38%，61%)，批量购买（34，55%）和跟踪交付（30，48%）的折扣。许多网站表示SCRA产品是：不供人类消费（41，66％），仅用于研究目的(15%，24%)，或合法（28，45%）。网站销售的中位数（IQR）为16（7-25）SCRAvaping品牌。几乎所有的瓶子都是vaping液体（1220/1225，99.6％）。最常见的瓶子尺寸为5mL（60％），每次销售的SCRA液体的中位数（IQR）总体积为50mL（10-200mL）。中位数（IQR）价格为3.39英镑/mL（2.01英镑/mL-5.29英镑/mL）。价格随着购买量的增加而下降(≤5mL，6.58英镑/mL，>200mL的1.60英镑/mL）。
结论：SCRAvaping产品很容易在线获得，小批量和散装。向购买者提供的有关安全性和合法性的信息缺乏或具有误导性。需要进一步的研究来证实这些产品的化学性质。政策制定者应考虑采取步骤限制购买和使用这些产品所造成的潜在危害。
