Abstract：
An 11-year-old female was referred from an outside institution after a diagnostic biopsy and subsequent excision of a progressively enlarging reddish-brown nodule demonstrated features concerning for a balloon cell nevus with severe atypia versus a high-grade melanocytoma. Upon review of the initial biopsy specimen and molecular data, we favored the diagnosis to be consistent with a high-grade melanocytoma with balloon cell changes while considering the possibility of balloon cell melanoma due to concerning histopathologic and genetic abnormalities. In this case study, we discuss critical diagnostic considerations in this rare pediatric case and highlight important pathologic and clinical features of melanocytomas and balloon cell melanoma.
摘要：
在进行诊断性活检并随后切除逐渐扩大的红棕色结节后，一名11岁的女性从外部机构转诊，这表明球囊细胞痣具有严重的异型性与高度黑色素细胞瘤有关。在查看初始活检标本和分子数据后，我们认为该诊断与高度黑色素细胞瘤伴球囊细胞改变相一致,同时考虑到由于组织病理学和遗传异常而导致的球囊细胞黑色素瘤的可能性.在这个案例研究中,我们讨论了这个罕见的儿科病例的关键诊断考虑因素，并强调了黑色素细胞瘤和球囊细胞黑色素瘤的重要病理和临床特征。
