Abstract：
Polyoxometalates (POMs) have drawn significant attention on account of their structural designability, compositional diversity and great potential applications. As an indispensable branch of POMs, selenotungstates (SeTs) have been synthesized extensively. Some SeTs have been applied as sensing materials for detecting biomarkers (e.g., metabolites, hormones, cancer markers). To gain a comprehensive understanding of advancements in SeT-based sensing materials, we present an overview that encapsulates the sensing performances and mechanisms of SeT-based biosensors. SeT-based biosensors are categorized into electrochemical catalytic biosensors, electrochemical affinity biosensors, \"turn-off\" fluorescence biosensors and \"turn-on\" fluorescence biosensors. We anticipate the expansive potential of SeT-based biosensors in wearable and implantable sensing technologies, which promises to catalyze significant breakthroughs in SeT-based biosensors.
摘要：
多金属氧酸盐（POM）由于其结构可设计性而引起了极大的关注，成分多样性和巨大的潜在应用。作为POM不可或缺的分支，硒钨酸盐(SeTs)已被广泛合成。一些SeT已被用作检测生物标志物的传感材料(例如，代谢物，荷尔蒙，癌症标志物)。为了全面了解基于SeT的传感材料的进步，我们概述了基于SeT的生物传感器的传感性能和机理。基于SeT的生物传感器分为电化学催化生物传感器，电化学亲和生物传感器，“关闭”荧光生物传感器和“打开”荧光生物传感器。我们预计基于SeT的生物传感器在可穿戴和可植入传感技术中的广阔潜力，有望促进基于SeT的生物传感器的重大突破。
