Abstract：
Serotonin syndrome (SS) is a life-threatening condition caused by serotonergic medications. We describe a unique case of SS likely caused by prolonged exposure to propofol and remifentanil alone. A young male presented for vestibular schwannoma resection. Several hours into the case, the patient demonstrated hyperthermia and hemodynamic instability, followed by clonus, rigidity, shivering, and tachycardia after emergence. SS was diagnosed using Hunter\'s criteria and improved with supportive measures. While the patient endorsed a history of methamphetamine use, his urine drug screen was negative. The possibility of SS should be considered when administering propofol and remifentanil, particularly with prolonged infusions.
摘要：
5-羟色胺综合征（SS）是由5-羟色胺能药物引起的危及生命的疾病。我们描述了一个独特的SS病例，可能是由于长时间暴露于丙泊酚和瑞芬太尼引起的。一名年轻男性接受前庭神经鞘瘤切除术。几个小时后，患者表现出热疗和血流动力学不稳定，其次是克洛诺斯，刚性,颤抖,出现后的心动过速.使用Hunter的标准诊断SS，并通过支持措施改善。虽然患者认可了甲基苯丙胺的使用史，他的尿液药物筛查呈阴性。丙泊酚和瑞芬太尼给药时，应考虑SS的可能性，尤其是长时间的输液。
