PDF(Pubmed)
Abstract：
Colorectal cancer (CRC) is a significant global health burden, being the third leading cancer globally. Its incidence has been observed to be higher in developed regions such as North America and Europe with geographical variations in mortality rates. Efforts to address this disease burden include promoting early detection through screening and implementing treatment strategies to improve patient outcomes. With the growing and aging population, the incidence of CRC will undoubtedly increase. These epidemiological trends will mean that healthcare professionals will increasingly encounter CRC in more complex patients. Hence, it becomes imperative to have a deeper appreciation of the pathophysiology of CRC and understand the intricate interplay between a patient\'s physiology and their goals of care before offering treatment. This review article will aim to encapsulate the important nuances and perspectives of managing this disease in the context of an elderly patient.
摘要：
结直肠癌（CRC）是一个重大的全球健康负担，成为全球第三大癌症。据观察，在北美和欧洲等发达地区，其发病率较高，死亡率存在地理差异。解决这种疾病负担的努力包括通过筛查促进早期检测和实施治疗策略以改善患者预后。随着人口的不断增长和老龄化,CRC的发病率无疑会增加。这些流行病学趋势将意味着医疗保健专业人员将越来越多地在更复杂的患者中遇到CRC。因此，在提供治疗前,我们必须更深入地了解CRC的病理生理学,了解患者的生理和他们的治疗目标之间复杂的相互作用.这篇综述文章旨在总结在老年患者的情况下管理这种疾病的重要细微差别和观点。
