PDF(Pubmed)
Abstract：
The prevalence of diabetes mellitus and its associated complications, particularly diabetic foot pathologies, poses significant healthcare challenges and economic burdens globally. This review synthesises current evidence on the surgical management of the diabetic foot, focusing on the interplay between neuropathy, ischemia, and infection that commonly culminates in ulcers, infections, and, in severe cases, amputations. The escalating incidence of diabetes mellitus underscores the urgency for effective management strategies, as diabetic foot complications are a leading cause of hospital admissions among diabetic patients, significantly impacting morbidity and mortality rates. This review explores the pathophysiological mechanisms underlying diabetic foot complications and further examines diabetic foot ulcers, infections, and skeletal pathologies such as Charcot arthropathy, emphasising the critical role of early diagnosis, comprehensive management strategies, and interdisciplinary care in mitigating adverse outcomes. In addressing surgical interventions, this review evaluates conservative surgeries, amputations, and reconstructive procedures, highlighting the importance of tailored approaches based on individual patient profiles and the specific characteristics of foot pathologies. The integration of advanced diagnostic tools, novel surgical techniques, and postoperative care, including offloading and infection control, are discussed in the context of optimising healing and preserving limb function.
摘要：
糖尿病及其相关并发症的患病率，特别是糖尿病足病变，在全球范围内带来了巨大的医疗保健挑战和经济负担。这篇综述综合了糖尿病足手术治疗的最新证据，关注神经病之间的相互作用，缺血,和通常以溃疡告终的感染，感染,and,在严重的情况下，截肢。糖尿病发病率的上升强调了有效管理策略的紧迫性，由于糖尿病足并发症是糖尿病患者入院的主要原因，显着影响发病率和死亡率。这篇综述探讨了糖尿病足并发症的病理生理机制，并进一步研究了糖尿病足溃疡。感染,和骨骼病理学，如Charcot关节病，强调早期诊断的关键作用，综合管理策略，和跨学科护理在减轻不良后果。在解决外科手术时，这篇综述评估了保守手术，截肢,和重建程序，强调基于个体患者概况和足部病理的具体特征的定制方法的重要性。集成先进的诊断工具，新颖的手术技术，和术后护理，包括卸载和感染控制，在优化愈合和保持肢体功能的背景下进行了讨论。
