Abstract:
Chronic recurrent multifocal osteomyelitis is a rare auto-inflammatory disease in children, with only a few reports of its association with other inflammatory diseases, such as systemic juvenile idiopathic arthritis. A 15-year-old boy was admitted due to fever, skin rash, arthritis, and high inflammatory factors and was finally diagnosed with systemic juvenile idiopathic arthritis. After 6 months of recovery from the disease, the patient was referred due to local pain and swelling in the arms and left thigh. In radiography, bone lesions were seen in the shoulders, left humerus, and left femoral diaphysis. A whole-body bone scan showed increased absorption in these areas, which suggested a tumor or osteomyelitis. A biopsy of the bone lesion of the left humerus confirmed sterile osteomyelitis. Although the co-incidence of chronic recurrent multifocal osteomyelitis with systemic juvenile idiopathic arthritis is rare, it should be considered in differential diagnosis.
摘要:
慢性复发性多灶性骨髓炎是一种罕见的儿童自身炎症性疾病,只有少数报道它与其他炎症性疾病有关,如系统性幼年特发性关节炎。一名十五岁男童因发烧入院,皮疹,关节炎,和高炎症因子,最终被诊断为系统性幼年特发性关节炎。从疾病中恢复6个月后,由于手臂和左大腿局部疼痛和肿胀,患者被转诊。在射线照相中,在肩膀上看到了骨损伤,左肱骨,和左股骨骨干.全身骨骼扫描显示这些区域的吸收增加,提示肿瘤或骨髓炎.左肱骨骨病变的活检证实了无菌性骨髓炎。尽管慢性复发性多灶性骨髓炎合并系统性幼年特发性关节炎的情况很少见,在鉴别诊断中应考虑。