PDF(Pubmed)
Abstract：
UNASSIGNED: Subpleural located pulmonary nodules are perioperatively invisible to the surgeon. Their precise identification is conventionally possible by palpation, but often at the cost of performing a thoracotomy. The aim of the study was to evaluate the success rate and feasibility of the pre-operative CT-guided marking subpleural localized nodule using a mixture of Patent Blue V and an iodine contrast agent prior to the extra-anatomical video-assisted thoracoscopic surgery (VATS) resection in patients for whom the primary anatomical resection in terms of segmentectomy or lobectomy was not indicated.
UNASSIGNED: The data of consecutive patients with pulmonary nodules located ≤ 30 mm from the parietal pleura, who were indicated for VATS extra-anatomical resection between 2017 to 2023, were retrospectively reviewed and analyzed. All patients indicated for VATS resection underwent color marking of the area with the pulmonary lesion under CT-guided control immediately before the surgery. The primary outcome was the marking success. Morphological lesion characteristics, time from marking to the surgery, procedure related complications, final histology findings and 30day mortality were analyzed. Additionally, we assessed the association of the successful marking and the patient\'s smoking history.
UNASSIGNED: A total of 62 lesions were marked. The successful marking was observed in 56/62 (90.3%) patients. The median time from the lesion marking to the beginning of surgery was 75.0 (IQR 65.0-85.0) minutes. The procedure related pneumothorax was observed in 6 (9.7%) patients, intraparenchymal hematoma in 1 (1.6%) patient. No statistically significant association of the depth of the subpleural lesion\'s location, occurrence of complications or time from the marking to surgery and the successful marking was observed. The 30day mortality was zero. No association of smoking and successful marking was observed.
UNASSIGNED: The method of marking the subpleural pulmonary lesions under CT-guided control with a mixture of Patent Blue V and iodine contrast agent is a safe and effective method with minimal complications. It provides surgeons the precise visualization of the affected pulmonary parenchyma before the planned extra-anatomical VATS resection.
UNASSIGNED: The data of consecutive patients with pulmonary nodules located ≤ 30 mm from the parietal pleura, who were indicated for VATS extra-anatomical resection between 2017 to 2023, were retrospectively reviewed and analyzed. All patients indicated for VATS resection underwent color marking of the area with the pulmonary lesion under CT-guided control immediately before the surgery. The primary outcome was the marking success. Morphological lesion characteristics, time from marking to the surgery, procedure related complications, final histology findings and 30day mortality were analyzed. Additionally, we assessed the association of the successful marking and the patient\'s smoking history.
UNASSIGNED: A total of 62 lesions were marked. The successful marking was observed in 56/62 (90.3%) patients. The median time from the lesion marking to the beginning of surgery was 75.0 (IQR 65.0-85.0) minutes. The procedure related pneumothorax was observed in 6 (9.7%) patients, intraparenchymal hematoma in 1 (1.6%) patient. No statistically significant association of the depth of the subpleural lesion\'s location, occurrence of complications or time from the marking to surgery and the successful marking was observed. The 30day mortality was zero. No association of smoking and successful marking was observed.
UNASSIGNED: The method of marking the subpleural pulmonary lesions under CT-guided control with a mixture of Patent Blue V and iodine contrast agent is a safe and effective method with minimal complications. It provides surgeons the precise visualization of the affected pulmonary parenchyma before the planned extra-anatomical VATS resection.
摘要：
■位于胸膜下的肺结节对外科医生来说是围手术期看不见的。他们的精确识别通常可以通过触诊进行，但通常以进行开胸手术为代价。该研究的目的是评估术前使用专利蓝V和碘对比剂的混合物进行CT引导标记胸膜下局部结节的成功率和可行性，然后进行解剖外视频辅助胸腔镜手术（VATS）切除。未进行节段切除术或肺叶切除术的患者。
■连续肺结节位于距顶叶胸膜≤30mm的患者的数据，对2017年至2023年期间接受VATS解剖外切除手术的患者进行回顾性回顾和分析.所有需要进行VATS切除的患者在手术前立即在CT引导下进行肺部病变区域的彩色标记。主要结果是标记成功。形态学病变特征,从标记到手术的时间，手术相关并发症,分析了最终的组织学发现和30天的死亡率.此外,我们评估了成功标记与患者吸烟史的相关性.
■共标记了62个病灶。在56/62（90.3％）患者中观察到成功的标记。从病变标记到手术开始的中位时间为75.0（IQR65.0-85.0）分钟。6例(9.7%)患者出现手术相关气胸,1例（1.6％）患者的实质内血肿。胸膜下病变位置的深度无统计学意义的关联，观察到从标记到手术的并发症或时间以及成功标记。30天死亡率为零。没有观察到吸烟和成功标记的关联。
■用专利蓝V和碘造影剂的混合物在CT引导的控制下标记胸膜下肺部病变的方法是一种安全有效的方法，并发症最少。在计划的解剖外VATS切除之前，它为外科医生提供了受影响的肺实质的精确可视化。
■连续肺结节位于距顶叶胸膜≤30mm的患者的数据，对2017年至2023年期间接受VATS解剖外切除手术的患者进行回顾性回顾和分析.所有需要进行VATS切除的患者在手术前立即在CT引导下进行肺部病变区域的彩色标记。主要结果是标记成功。形态学病变特征,从标记到手术的时间，手术相关并发症,分析了最终的组织学发现和30天的死亡率.此外,我们评估了成功标记与患者吸烟史的相关性.
■共标记了62个病灶。在56/62（90.3％）患者中观察到成功的标记。从病变标记到手术开始的中位时间为75.0（IQR65.0-85.0）分钟。6例(9.7%)患者出现手术相关气胸,1例（1.6％）患者的实质内血肿。胸膜下病变位置的深度无统计学意义的关联，观察到从标记到手术的并发症或时间以及成功标记。30天死亡率为零。没有观察到吸烟和成功标记的关联。
■用专利蓝V和碘造影剂的混合物在CT引导的控制下标记胸膜下肺部病变的方法是一种安全有效的方法，并发症最少。在计划的解剖外VATS切除之前，它为外科医生提供了受影响的肺实质的精确可视化。
