PDF(Pubmed)
Abstract：
BACKGROUND: The influence of maternal oral and dental health on the occurrence of Preterm Premature Rupture of Membranes (P-PROM) and its underlying mechanisms remain uncertain. This research seeks to investigate the impact of maternal oral and dental health on the incidence of P-PROM and its association with inflammatory markers in the blood.
METHODS: This study adopts a prospective case-control design methodology. The study involved 70 women diagnosed with P-PROM and delivered by an obstetrician and 79 women who had healthy deliveries with no prenatal complications. The values for DMFT (Number of decayed, missing and filled teeth) index, Gingival Index (GI), Plaque index (PI), Pocket depth (PD), Clinical attachment loss (CAL) and medical history were recorded. Mann-Whitney U test and hierarchical binomial logistic regression analysis were applied. It was considered statistically significant at p < 0.05.
RESULTS: The case group\'s DMFT, PI, GI, PD values were statistically significantly higher than the control group (p < 0.001). There was no relationship between DMFT, GI, PD, CAL and inflammatory blood markers (p > 0.05). In the regression analysis for possible risk factors that may be effective in P-PROM, oral and dental health parameters were the most effective.
CONCLUSIONS: Oral and dental health of women with P-PROM was found to be worse than that of the control group. Oral and dental health may be a potential risk factor that may contribute to adverse pregnancy outcomes associated with P-PROM.
METHODS: This study adopts a prospective case-control design methodology. The study involved 70 women diagnosed with P-PROM and delivered by an obstetrician and 79 women who had healthy deliveries with no prenatal complications. The values for DMFT (Number of decayed, missing and filled teeth) index, Gingival Index (GI), Plaque index (PI), Pocket depth (PD), Clinical attachment loss (CAL) and medical history were recorded. Mann-Whitney U test and hierarchical binomial logistic regression analysis were applied. It was considered statistically significant at p < 0.05.
RESULTS: The case group\'s DMFT, PI, GI, PD values were statistically significantly higher than the control group (p < 0.001). There was no relationship between DMFT, GI, PD, CAL and inflammatory blood markers (p > 0.05). In the regression analysis for possible risk factors that may be effective in P-PROM, oral and dental health parameters were the most effective.
CONCLUSIONS: Oral and dental health of women with P-PROM was found to be worse than that of the control group. Oral and dental health may be a potential risk factor that may contribute to adverse pregnancy outcomes associated with P-PROM.
摘要：
背景：母亲口腔和牙齿健康对未足月早破（P-PROM）发生的影响及其潜在机制仍不确定。这项研究旨在调查母亲口腔和牙齿健康对P-PROM发生率的影响及其与血液中炎症标志物的关联。
方法：本研究采用前瞻性病例对照设计方法。该研究涉及70名诊断为P-PROM并由产科医生分娩的妇女和79名健康分娩且没有产前并发症的妇女。DMFT(衰减数,缺失和填充的牙齿)索引，牙龈指数(GI),斑块指数(PI),口袋深度（PD），记录临床依恋丧失（CAL）和病史。采用Mann-WhitneyU检验和分层二项逻辑回归分析。在p<0.05时被认为是统计学上显著的。
结果：病例组的DMFT，PI,GI,PD值均显著高于对照组(p<0.001)。DMFT之间没有关系，GI,PD,CAL和炎性血液标志物(p>0.05)。在对P-PROM中可能有效的可能风险因素的回归分析中，口腔和牙齿健康参数是最有效的。
结论：发现P-PROM妇女的口腔和牙齿健康状况比对照组差。口腔和牙齿健康可能是导致与P-PROM相关的不良妊娠结局的潜在危险因素。
方法：本研究采用前瞻性病例对照设计方法。该研究涉及70名诊断为P-PROM并由产科医生分娩的妇女和79名健康分娩且没有产前并发症的妇女。DMFT(衰减数,缺失和填充的牙齿)索引，牙龈指数(GI),斑块指数(PI),口袋深度（PD），记录临床依恋丧失（CAL）和病史。采用Mann-WhitneyU检验和分层二项逻辑回归分析。在p<0.05时被认为是统计学上显著的。
结果：病例组的DMFT，PI,GI,PD值均显著高于对照组(p<0.001)。DMFT之间没有关系，GI,PD,CAL和炎性血液标志物(p>0.05)。在对P-PROM中可能有效的可能风险因素的回归分析中，口腔和牙齿健康参数是最有效的。
结论：发现P-PROM妇女的口腔和牙齿健康状况比对照组差。口腔和牙齿健康可能是导致与P-PROM相关的不良妊娠结局的潜在危险因素。
