关键词: Alveolar augmentation Alveolar bone defects Bone graft Dentin Medicine Tissue engineering

来  源:   DOI:10.1016/j.jobcr.2024.05.005   PDF(Pubmed)

Abstract:
UNASSIGNED: Application of alveolar bone graft (ABG) in alveolar augmentation is done to prevent excessive bone resorption due to tooth extraction, missing teeth, or other diseases/conditions affecting the alveolar bone. The use of autogenous dentin-derived ABG has been considered as the composition of dentin appears to be nearly analogous to that of bone.
UNASSIGNED: This systematic review aims to assess the efficacy of dentin-derived ABG for alveolar augmentation of post-extraction sockets or other alveolar bone defects by evaluating volume gain and histomorphometric data.
UNASSIGNED: A search of systematic literature was conducted in Pubmed, Scopus, Web of Science, and Embase from database inception to October 2023. The review included both randomized controlled trials (RCT), pilot studies, clinical trials, and retrospective studies reporting on dentin-derived ABG use for alveolar augmentation.
UNASSIGNED: Overall, 298 articles were obtained from the initial search. From these articles, 21 articles met the inclusion criteria and were included for descriptive analysis. All of the studies indicated low risk of bias. Studies of dentin-derived ABG, which used bone-derived grafts as the control group, have shown significantly higher percentages of new bone formation, gain in vertical and horizontal dimensions, and less reduction in dimensions.
UNASSIGNED: Dentin-derived ABG was effective in volume maintenance, indicating promising results via histomorphometric and radiographic analysis.
摘要:
牙槽骨移植(ABG)在牙槽增强中的应用是为了防止由于拔牙而导致的过度骨吸收,缺失的牙齿,或影响牙槽骨的其他疾病/状况。已经认为使用自体牙本质衍生的ABG,因为牙本质的组成似乎与骨的组成几乎相似。
本系统综述旨在通过评估体积增加和组织形态学数据来评估牙本质衍生的ABG对拔牙后牙槽腔或其他牙槽骨缺损的牙槽增强的功效。
在Pubmed,Scopus,WebofScience,和Embase从数据库开始到2023年10月。该综述包括两项随机对照试验(RCT),试点研究,临床试验,和回顾性研究报告牙本质衍生的ABG用于肺泡扩张。
总的来说,最初检索获得298篇文章。从这些文章中,21篇文章符合纳入标准,纳入进行描述性分析。所有研究都表明偏倚风险较低。牙本质衍生的ABG的研究,使用骨源性移植物作为对照组,已经显示出明显更高的新骨形成百分比,垂直和水平维度的增益,尺寸减少。
牙本质衍生的ABG在容量维持方面有效,通过组织形态学和影像学分析表明有希望的结果。
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