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Abstract：
Introduction Peritonitis refers to the inflammation of the peritoneum and peritoneal cavity. Causes of peritonitis can be bacterial (gastrointestinal or non-gastrointestinal), chemical, traumatic, or ischemic. Peritonitis can be localized or diffuse, acute or chronic. Peritonitis can be primary, secondary, or tertiary, according to the pathogenesis. Peritonitis developed secondary to hollow viscus perforation is a life-threatening condition and a common cause of emergency surgery in India. The Mannheim peritonitis index (MPI) is a simple scoring system that can accurately predict the outcome of peritonitis. This study aimed to evaluate the effectiveness of MPI in predicting mortality risk or prognosis in patients with peritonitis due to hollow viscus perforation. Materials and methods This observational cross-sectional study at the Department of General Surgery, Rajendra Institute of Medical Sciences, Ranchi, involved 111 patients with peritonitis due to hollow viscus perforation from December 2021 to March 2022. Detailed history, clinical examination, relevant blood tests, and radiological investigations established a diagnosis of perforation peritonitis, followed by a score assessment. Data were analyzed using SPSS software (IBM Corp., Armonk, NY, USA). Results Patients >50 years had higher mortality (i.e., 18/43) than patients <50 years (i.e., 13/68). Overall mortality was 31, which included one in low risk, 12 in intermediate risk, and 18 in the high-risk group. Mortality was lowest in the low-risk group (i.e., 1/30), highest in the high-risk group (i.e., 18/40), and 12/41 in the intermediate-risk group; the p-value was <0.05, which was highly significant. Mortality was higher in patients presenting after 24 hours, having organ failure, and non-colonic sepsis. Conclusion The MPI scoring system is simple, easy to calculate, cost-effective, precise, and effective in assessing mortality and morbidity risk in patients with peritonitis due to hollow viscus perforation. It can also guide further management strategies.
摘要：
引言腹膜炎是指腹膜和腹膜腔的炎症。腹膜炎的原因可以是细菌（胃肠道或非胃肠道），化学,创伤性,或缺血。腹膜炎可以是局限性的或弥漫性的，急性或慢性。腹膜炎可以是原发性的，次要,或第三级，根据发病机理。在印度，内脏空洞穿孔继发的腹膜炎是危及生命的疾病，也是急诊手术的常见原因。曼海姆腹膜炎指数（MPI）是一种简单的评分系统，可以准确预测腹膜炎的预后。本研究旨在评估MPI在预测中空脏器穿孔引起的腹膜炎患者的死亡风险或预后中的有效性。材料和方法这项在普外科进行的观察性横断面研究，Rajendra医学科学研究所,兰契,纳入了2021年12月至2022年3月111例因内脏空洞穿孔引起的腹膜炎患者.详细的历史,临床检查,相关血液检查,放射学检查确定了穿孔性腹膜炎的诊断，然后是分数评估。使用SPSS软件(IBMCorp.,Armonk,NY,美国）。结果>50岁的患者死亡率较高(即18/43)比患者<50岁(即，13/68)。总死亡率为31，其中包括一个低风险，12在中等风险中，高危人群为18人。死亡率在低风险组中最低(即，1/30),在高风险组中最高(即，18/40),中危组为12/41；p值<0.05，具有高度显著性。24小时后出现的患者死亡率较高，器官衰竭,和非结肠败血症.结论MPI评分系统简单,易于计算，成本效益高,精确，并有效评估因内脏空洞穿孔引起的腹膜炎患者的死亡率和发病率风险。它还可以指导进一步的管理策略。
