关键词: Case report Cerebrospinal fluid Herpes simplex virus Memory affection Polymerase chain reaction

来  源:   DOI:10.1016/j.idcr.2024.e01981   PDF(Pubmed)

Abstract:
Herpes simplex encephalitis (HSVE) is a potentially fatal infectious central nervous system (CNS) disorder. Thus, early detection is critical in determining the case\'s fate. Clinical history and examination, brain computed tomography, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and lumbar puncture have been used to establish a diagnosis. This report describes a case of HSVE with hypocellular cerebrospinal fluid (CSF) and an uncommon form of memory impairment. However, MRI results were consistent with HSVE, and CSF PCR tested positive for HSV-1 DNA that responded to treatment. We routinely advise patients to begin antiviral therapy as soon as possible to avoid complications.
摘要:
单纯疱疹性脑炎(HSVE)是一种潜在致命的传染性中枢神经系统(CNS)疾病。因此,早期发现是决定案件命运的关键。临床病史和检查,脑计算机断层扫描,动态对比增强磁共振成像(DCE-MRI),腰椎穿刺已经被用来建立诊断。本报告描述了一例HSVE,伴有低细胞脑脊液(CSF)和罕见的记忆障碍。然而,MRI结果与HSVE一致,和CSFPCR检测对治疗有反应的HSV-1DNA呈阳性。我们通常建议患者尽快开始抗病毒治疗,以避免并发症。
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