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Abstract：
BACKGROUND: Despite several preventative and control measures Ethiopia continues to see an increase in cervical cancer. Comprehensive evidence is very important to suggest ministry of health. Therefore, the aim of this study is to estimate the pooled violence of Precancerous Cervical Lesion and to identify associated factors among women living with HIV AIDS in Ethiopia.
METHODS: From February 15, 2024 to March 17, 2024, systematic and methodical search of the literature was conducted using electronic databases such as PubMed, HINARI, Global Health, Scopus, EMBASE, Web of Science, African Journal online (AJOL), and Google Scholar. Quality appraisal was assessed based on Joanna Briggs Institute (JBI) critical appraisal checklist for analytical cross-sectional study using 9 criteria. The Cochrane Q and I2 test statistics were used to verify the heterogeneity of the studies. Using a fixed effect model, the pooled estimate prevalence of precancerous cervical lesion among women living with HIV was calculated.
RESULTS: After reviewing 9,470 studies, 9 studies involving 2,910 women with HIV were included. The pooled estimate of precancerous cervical cancer among women living with HIV in Ethiopia was 15.34% (95% CI: 8.97, 21.72). Having history of sexual infection (POR = 3.12; 95% CI: 1.38, 7.05), having multiple sexual partner (POR = 3.14; 95% CI: 2.29, 4.30), and parity greater than two (POR = 4.97; 95% CI: 3.17, 7.78) were identified factors associated with precancerous cervical lesion.
CONCLUSIONS: This study found that about one-six of HIV-positive women developed precancerous cervical lesion. According to this study, there was a substantial correlation between precancerous cervical lesion among HIV-positive women and having history of sexually transmitted infection, having multiple sexual partners, and being multipara. In order to reduce precancerous cervical lesion, FMOH, policy makers, and interested parties should pay particular attention to this issue.
METHODS: From February 15, 2024 to March 17, 2024, systematic and methodical search of the literature was conducted using electronic databases such as PubMed, HINARI, Global Health, Scopus, EMBASE, Web of Science, African Journal online (AJOL), and Google Scholar. Quality appraisal was assessed based on Joanna Briggs Institute (JBI) critical appraisal checklist for analytical cross-sectional study using 9 criteria. The Cochrane Q and I2 test statistics were used to verify the heterogeneity of the studies. Using a fixed effect model, the pooled estimate prevalence of precancerous cervical lesion among women living with HIV was calculated.
RESULTS: After reviewing 9,470 studies, 9 studies involving 2,910 women with HIV were included. The pooled estimate of precancerous cervical cancer among women living with HIV in Ethiopia was 15.34% (95% CI: 8.97, 21.72). Having history of sexual infection (POR = 3.12; 95% CI: 1.38, 7.05), having multiple sexual partner (POR = 3.14; 95% CI: 2.29, 4.30), and parity greater than two (POR = 4.97; 95% CI: 3.17, 7.78) were identified factors associated with precancerous cervical lesion.
CONCLUSIONS: This study found that about one-six of HIV-positive women developed precancerous cervical lesion. According to this study, there was a substantial correlation between precancerous cervical lesion among HIV-positive women and having history of sexually transmitted infection, having multiple sexual partners, and being multipara. In order to reduce precancerous cervical lesion, FMOH, policy makers, and interested parties should pay particular attention to this issue.
摘要：
背景：尽管采取了一些预防和控制措施，但埃塞俄比亚的宫颈癌仍在增加。全面的证据对卫生部的建议非常重要。因此,本研究的目的是评估埃塞俄比亚宫颈癌前病变的合并暴力行为,并确定感染HIV-AIDS的妇女的相关因素.
方法：从2024年2月15日至2024年3月17日，使用诸如PubMed，Hinari,全球卫生,Scopus,EMBASE,WebofScience,非洲在线杂志（AJOL），谷歌学者。质量评估是根据JoannaBriggs研究所（JBI）关键评估清单评估的，用于分析性横断面研究，使用9个标准。采用CochraneQ和I2检验统计量验证研究的异质性。使用固定效果模型，我们计算了HIV感染女性宫颈癌前病变的合并估计患病率.
结果：在回顾了9,470项研究之后，包括9项研究，涉及2,910名感染艾滋病毒的妇女。埃塞俄比亚感染艾滋病毒的妇女中宫颈癌前病变的汇总估计为15.34%(95%CI:8.97,21.72)。有性感染史（POR=3.12；95%CI：1.38，7.05），有多个性伴侣（POR=3.14；95%CI：2.29，4.30），和胎次大于2（POR=4.97；95％CI：3.17，7.78）是与宫颈癌前病变相关的确定因素。
结论：这项研究发现，大约有1/6的HIV阳性妇女出现了宫颈癌前病变。根据这项研究,HIV阳性妇女的宫颈癌前病变与有性传播感染史之间存在实质性相关性，有多个性伴侣,并且是多段。为了减少宫颈癌前病变，FMOH,政策制定者,有关各方应特别注意这个问题。
方法：从2024年2月15日至2024年3月17日，使用诸如PubMed，Hinari,全球卫生,Scopus,EMBASE,WebofScience,非洲在线杂志（AJOL），谷歌学者。质量评估是根据JoannaBriggs研究所（JBI）关键评估清单评估的，用于分析性横断面研究，使用9个标准。采用CochraneQ和I2检验统计量验证研究的异质性。使用固定效果模型，我们计算了HIV感染女性宫颈癌前病变的合并估计患病率.
结果：在回顾了9,470项研究之后，包括9项研究，涉及2,910名感染艾滋病毒的妇女。埃塞俄比亚感染艾滋病毒的妇女中宫颈癌前病变的汇总估计为15.34%(95%CI:8.97,21.72)。有性感染史（POR=3.12；95%CI：1.38，7.05），有多个性伴侣（POR=3.14；95%CI：2.29，4.30），和胎次大于2（POR=4.97；95％CI：3.17，7.78）是与宫颈癌前病变相关的确定因素。
结论：这项研究发现，大约有1/6的HIV阳性妇女出现了宫颈癌前病变。根据这项研究,HIV阳性妇女的宫颈癌前病变与有性传播感染史之间存在实质性相关性，有多个性伴侣,并且是多段。为了减少宫颈癌前病变，FMOH,政策制定者,有关各方应特别注意这个问题。
