Abstract:
Diabesity is a condition where an individual has both diabetes and obesity, which can lead to severe complications including cardiovascular disease, a leading cause of mortality. Recently, cancer has become a leading cause of excess hospitalizations, and both diabetes and obesity are associated with a higher risk of developing several types of cancer. In this review, we propose that chronic stress significantly increases this association. Managing diabetes and obesity is challenging as they both cause significant distress. The relationship between stress and cancer is interconnected, with anxiety and depression being common in cancer patients. Cancer diagnosis and treatment can cause lasting changes in the body\'s neuroendocrine system, with stress causing an excessive release of catecholamines and prostaglandins in patients undergoing cancer surgery, which promotes the spread of cancer to other parts of the body. Furthermore, stress could significantly increase the risk of cancer in patients with diabetes, obesity, or both.
摘要:
肥胖是指个体同时患有糖尿病和肥胖的疾病,这可能导致严重的并发症,包括心血管疾病,死亡的主要原因.最近,癌症已经成为过度住院的主要原因,糖尿病和肥胖都与几种癌症的高风险相关。在这次审查中,我们认为慢性应激会显著增加这种关联.管理糖尿病和肥胖症具有挑战性,因为它们都会引起严重的痛苦。压力和癌症之间的关系是相互关联的,焦虑和抑郁在癌症患者中很常见。癌症的诊断和治疗可以引起人体神经内分泌系统的持久变化,在接受癌症手术的患者中,由于压力导致儿茶酚胺和前列腺素的过度释放,促进癌症扩散到身体的其他部位。此外,压力会显著增加糖尿病患者患癌症的风险,肥胖,或者两者兼而有之。