Abstract：
Cimex species are ectoparasites that exclusively feed on warm-blooded animals such as birds and mammals. Three cimicid species are known to be persistent pests for humans, including the tropical bed bug Cimex hemipterus, common bed bug Cimex lectularius, and Eastern bat bug Leptocimex boueti. To date, genomic information is restricted to the common bed bug C. lectularius, which limits understanding their biology and to provide controls of bed bug infestations. Here, a chromosomal-level genome assembly of C. hemipterus (495 Mb [megabase pairs]) contained on 16 pseudochromosomes (scaffold N50 = 34 Mb), together with 9 messenger RNA and small RNA transcriptomes were obtained. In comparison between hemipteran genomes, we found that the tetraspanin superfamily was expanded in the Cimex ancestor. This study provides the first genome assembly for the tropical bed bug C. hemipterus, and offers an unprecedented opportunity to address questions relating to bed bug infestations, as well as genomic evolution to hemipterans more widely.
摘要：
Cimex物种是外寄生虫，专门以温血动物如鸟类和哺乳动物为食。已知三种cimicid是人类的持久性害虫，包括热带臭虫Cimex半翅目，普通臭虫Cimexlectularius，和东部蝙蝠虫Leptocimexboueti。迄今为止,基因组信息仅限于常见的臭虫C.lectularius，这限制了对它们生物学的理解和对臭虫侵扰的控制。这里,包含在16个假染色体上的C.hemipterus（495Mb[兆碱基对]）的染色体水平基因组组装（支架N50=34Mb），获得了9个信使RNA和小RNA转录组。在半翅目基因组之间的比较，我们发现四跨膜蛋白超家族在Cimex祖先中扩展。这项研究为热带臭虫C.半翅目提供了第一个基因组组装，并提供了前所未有的机会来解决与臭虫侵扰有关的问题，以及更广泛的半翅目动物的基因组进化。
