PDF(Pubmed)
Abstract：
UNASSIGNED: Ovarian fibromas are benign tumours arising from the connective tissue of the ovarian cortex, classified into three pathological subtypes: fibroma, thecoma, and fibrothecoma. Their diagnosis is complicated by their solid nature and potential association with ascites and pleural effusion, resembling Meigs syndrome. Elevated serum CA125 levels can further complicate differentiation from malignant ovarian epithelial tumours.
METHODS: A 37-year-old female from a rural area presented with a distended abdomen and weight loss lasting 2 months. Clinical examinations revealed a solid pelvic mass and diagnostic tests showed significantly elevated CA125 levels. Imaging suggested a large ovarian mass and surgical intervention confirmed a fibrothecoma of the left ovary. The postoperative course was uneventful, with subsequent resolution of ascites and pleurisy.
UNASSIGNED: The diagnosis of ovarian fibromas/fibrothecomas poses challenges due to their asymptomatic nature, solid appearance, and occasional association with the Meigs syndrome. Elevated CA125 levels can mislead the diagnosis of epithelial ovarian carcinoma. The case underscores the importance of considering ovarian fibromas/fibrothecomas in the differential diagnosis of ovarian tumours with elevated CA125 levels, especially in women of reproductive age. The benign nature of these tumours necessitates a conservative surgical approach, emphasizing the importance of intraoperative frozen section analysis.
CONCLUSIONS: Ovarian fibrothecomas associated with elevated serum CA125 levels are rare. Their presentation can mimic malignant ovarian neoplasms, leading to potential diagnostic confusion. Surgical removal remains the treatment of choice, with a favorable prognosis post-surgery.
METHODS: A 37-year-old female from a rural area presented with a distended abdomen and weight loss lasting 2 months. Clinical examinations revealed a solid pelvic mass and diagnostic tests showed significantly elevated CA125 levels. Imaging suggested a large ovarian mass and surgical intervention confirmed a fibrothecoma of the left ovary. The postoperative course was uneventful, with subsequent resolution of ascites and pleurisy.
UNASSIGNED: The diagnosis of ovarian fibromas/fibrothecomas poses challenges due to their asymptomatic nature, solid appearance, and occasional association with the Meigs syndrome. Elevated CA125 levels can mislead the diagnosis of epithelial ovarian carcinoma. The case underscores the importance of considering ovarian fibromas/fibrothecomas in the differential diagnosis of ovarian tumours with elevated CA125 levels, especially in women of reproductive age. The benign nature of these tumours necessitates a conservative surgical approach, emphasizing the importance of intraoperative frozen section analysis.
CONCLUSIONS: Ovarian fibrothecomas associated with elevated serum CA125 levels are rare. Their presentation can mimic malignant ovarian neoplasms, leading to potential diagnostic confusion. Surgical removal remains the treatment of choice, with a favorable prognosis post-surgery.
摘要：
■卵巢纤维瘤是由卵巢皮质的结缔组织引起的良性肿瘤，分为三种病理亚型：纤维瘤，肿瘤,和纤维囊瘤.他们的诊断是复杂的，因为他们的固体性质和与腹水和胸腔积液的潜在关联，类似Meigs综合征.血清CA125水平升高可进一步使与恶性卵巢上皮性肿瘤的分化复杂化。
方法：一名来自农村地区的37岁女性表现为腹部扩张和体重下降，持续2个月。临床检查显示盆腔肿块坚实，诊断测试显示CA125水平显着升高。影像学提示卵巢肿块较大，手术干预证实左侧卵巢纤维腺瘤。术后进展顺利，随后腹水和胸膜炎的解决。
■卵巢纤维瘤/纤维瘤的诊断由于其无症状性质而面临挑战，坚固的外观,偶尔与Meigs综合征有关。CA125水平升高可误导上皮性卵巢癌的诊断。该病例强调了在CA125水平升高的卵巢肿瘤的鉴别诊断中考虑卵巢纤维瘤/纤维囊瘤的重要性。尤其是育龄妇女。这些肿瘤的良性性质需要保守的手术方法，强调术中冰冻切片分析的重要性。
结论：与血清CA125水平升高相关的卵巢纤维腺瘤是罕见的。它们的表现可以模仿恶性卵巢肿瘤，导致潜在的诊断混乱。手术切除仍然是首选的治疗方法，术后预后良好。
方法：一名来自农村地区的37岁女性表现为腹部扩张和体重下降，持续2个月。临床检查显示盆腔肿块坚实，诊断测试显示CA125水平显着升高。影像学提示卵巢肿块较大，手术干预证实左侧卵巢纤维腺瘤。术后进展顺利，随后腹水和胸膜炎的解决。
■卵巢纤维瘤/纤维瘤的诊断由于其无症状性质而面临挑战，坚固的外观,偶尔与Meigs综合征有关。CA125水平升高可误导上皮性卵巢癌的诊断。该病例强调了在CA125水平升高的卵巢肿瘤的鉴别诊断中考虑卵巢纤维瘤/纤维囊瘤的重要性。尤其是育龄妇女。这些肿瘤的良性性质需要保守的手术方法，强调术中冰冻切片分析的重要性。
结论：与血清CA125水平升高相关的卵巢纤维腺瘤是罕见的。它们的表现可以模仿恶性卵巢肿瘤，导致潜在的诊断混乱。手术切除仍然是首选的治疗方法，术后预后良好。
