关键词: EMR ESD GIT lesions Impedance Injection solution Polypectomy

Mesh : Electric Impedance Injections Humans Solutions Animals

来  源:   DOI:10.1007/s00109-024-02457-1   PDF(Pubmed)

Abstract:
In this work, for the first time, the specific impedances of various injection solutions as well as the surface and tissue impedance after injection of these solutions were analyzed and compared regarding the radio-frequency surgical cutting process. The impedances of 0.9% NaCl, 4% gelatine, 6% hydroxyethyl starch, 10% glycerol/5% fructose, 10% glucose, 5% and 20% albumin, blood, and blood plasma as well as aqua destillata have been tested in vitro. Even if EMR and ESD are routinely used in clinical practice, there is so far no easy, fast, and safe method to remove larger lesions en bloc. We show that the impedance of the injected solution shows to be a crucial factor for safe removal, especially of larger lesions (Ø > 20 mm) and more importantly in accordance with the requirements of oncology and pathology. KEY MESSAGES: Impedance is playing a crucial factor in the radio-frequency (RF)-surgery. With a higher Impedance there will be less current necessary to reach the aimed voltage. Injection solution Aqua destillata and 10% Glucose, show significantly higher Impedances. Higher impedances lead to less surgical related complications. Minor changes in existing method to improve patent safety.
摘要:
在这项工作中,第一次,分析了各种注射溶液的比阻抗以及注射这些溶液后的表面和组织阻抗,并比较了射频手术切割过程。0.9%NaCl的阻抗,4%明胶,6%羟乙基淀粉,10%甘油/5%果糖,10%葡萄糖,5%和20%白蛋白,血,和血浆以及水已经在体外进行了测试。即使在临床实践中常规使用EMR和ESD,到目前为止,没有什么容易的,快,和安全的方法来去除较大的病变。我们表明,注入溶液的阻抗是安全去除的关键因素,尤其是较大的病变(Ø>20毫米),更重要的是符合肿瘤学和病理学的要求。关键信息:阻抗在射频(RF)手术中起着至关重要的因素。在较高阻抗的情况下,将有较小的电流来达到目标电压。Aquadetillata和10%葡萄糖注射液,显示出明显更高的阻抗。较高的阻抗导致较少的手术相关并发症。对现有方法进行微小改变,以提高专利安全性。
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