PDF(Pubmed)
Abstract：
The reported incidence of blastomycosis is increasing in certain regions of the United States. The diagnosis is primarily made via urine antigen testing, culture, or cytology smear. The differential diagnosis for blastomycosis includes pneumonia, tuberculosis, and non-infectious pulmonary disease. Clinical context and epidemiologic exposure play a crucial role in diagnosis. However, the differential can expand significantly if there is disseminated central nervous system involvement, especially if pulmonary manifestations are not seen. Imaging begins to play a vital role when differentiating disseminated blastomycosis from other etiologies such as malignancy. Herein we present a case of a 58-year-old male who presented with seizures and right sided gaze preference found to have disseminated central nervous system blastomycosis. In this article, we will discuss symptoms and imaging findings of disseminated blastomycosis to help guide diagnosis and management.
摘要：
据报道，在美国某些地区，芽生菌病的发病率正在增加。诊断主要是通过尿液抗原检测，文化,或者细胞学涂片.芽生菌病的鉴别诊断包括肺炎，结核病,和非传染性肺病。临床背景和流行病学暴露在诊断中起着至关重要的作用。然而,如果有散布的中枢神经系统受累，差异可以显着扩大，特别是如果没有肺部表现。在将播散性胚真菌病与恶性肿瘤等其他病因区分开来时，影像学开始发挥至关重要的作用。在此，我们介绍了一例58岁的男性，该男性出现癫痫发作和右侧凝视偏好，发现已传播中枢神经系统胚芽真菌病。在这篇文章中,我们将讨论播散性芽生菌病的症状和影像学表现，以帮助指导诊断和治疗。
