PDF(Pubmed)
Abstract：
UNASSIGNED: To evaluate the role of Vitamin-D and calcium supplementation on preoperative weight reduction in obese women before laparoscopic ventral hernia repair.
UNASSIGNED: This double-blind clinical trial was conducted at the affiliated health centers of King Faisal University, Al-Ahsa, Saudi Arabia from January 2021 to December 2021. It included forty-five obese women aged 24-56 years, with body mass index (BMI) of 34.0-48.0kg/m2. They were randomly allocated into two groups; the Group-A (N=22) included obese women who received supplementation of 5000IU cholecalciferol (Vitamin-D3), and 1000mg calcium daily for 12 months, while the Group-B (N=23) received no treatment. Measurement of change in weight and BMI and comparison of their pre-operative weight reduction, laparoscopic operative time, and length of hospital stay was done.
UNASSIGNED: There were no differences in patients\' biographic data between the two groups. During the study, Vitamin-D level in the patients increased and there was a significant positive association with weight loss. In group-A, the mean weight loss was 11.8±3.5 kg. At the end of first year, their BMI decreased from 36.1±1.6kg/m2 at baseline to 29.7±2.6 kg/m2, whereas in-group-B, the mean weight loss was 6.8±3.1 kg and their BMI decreased from 36.9±2.69kg/m2 at baseline to 32.7±0.93kg/m2. The operation time and the length of hospital stay were shorter in group-A (107 vs.128.min) and (3 vs. 5 days) respectively as compared to Group-B.
UNASSIGNED: Vitamin-D and calcium supplementation contributes to a remarkable weight reduction of preoperative obese female patients, which in turn is associated with significantly better outcome of laparoscopic repair of ventral hernia.
UNASSIGNED: This double-blind clinical trial was conducted at the affiliated health centers of King Faisal University, Al-Ahsa, Saudi Arabia from January 2021 to December 2021. It included forty-five obese women aged 24-56 years, with body mass index (BMI) of 34.0-48.0kg/m2. They were randomly allocated into two groups; the Group-A (N=22) included obese women who received supplementation of 5000IU cholecalciferol (Vitamin-D3), and 1000mg calcium daily for 12 months, while the Group-B (N=23) received no treatment. Measurement of change in weight and BMI and comparison of their pre-operative weight reduction, laparoscopic operative time, and length of hospital stay was done.
UNASSIGNED: There were no differences in patients\' biographic data between the two groups. During the study, Vitamin-D level in the patients increased and there was a significant positive association with weight loss. In group-A, the mean weight loss was 11.8±3.5 kg. At the end of first year, their BMI decreased from 36.1±1.6kg/m2 at baseline to 29.7±2.6 kg/m2, whereas in-group-B, the mean weight loss was 6.8±3.1 kg and their BMI decreased from 36.9±2.69kg/m2 at baseline to 32.7±0.93kg/m2. The operation time and the length of hospital stay were shorter in group-A (107 vs.128.min) and (3 vs. 5 days) respectively as compared to Group-B.
UNASSIGNED: Vitamin-D and calcium supplementation contributes to a remarkable weight reduction of preoperative obese female patients, which in turn is associated with significantly better outcome of laparoscopic repair of ventral hernia.
摘要：
■评估在腹腔镜腹侧疝修补术前补充维生素D和钙对肥胖妇女术前体重减轻的作用。
■这项双盲临床试验是在费萨尔国王大学的附属健康中心进行的，Al-Ahsa,沙特阿拉伯从2021年1月到2021年12月。其中包括45名年龄在24-56岁之间的肥胖女性，体重指数（BMI）为34.0-48.0kg/m2。他们被随机分为两组；A组（N=22）包括接受5000IU胆钙化醇（维生素D3）补充的肥胖女性，和1000mg钙每天12个月，B组（N=23）未接受治疗。测量体重和BMI的变化及其术前体重减轻的比较，腹腔镜手术时间,并完成了住院时间。
■两组患者的传记资料没有差异。在研究期间,患者的维生素D水平增加，并且与体重减轻存在显着正相关。在A组中,平均体重减轻为11.8±3.5kg。在第一年年底，他们的BMI从基线时的36.1±1.6kg/m2下降到29.7±2.6kg/m2，而B组，平均体重减轻为6.8±3.1kg,BMI从基线时的36.9±2.69kg/m2降至32.7±0.93kg/m2.A组手术时间和住院时间均较短（107vs.128。分钟）和（3vs.5天)分别与B组相比。
■补充维生素D和钙有助于显着减轻术前肥胖女性患者的体重，这反过来又与腹腔镜腹疝修补术的效果明显更好相关。
■这项双盲临床试验是在费萨尔国王大学的附属健康中心进行的，Al-Ahsa,沙特阿拉伯从2021年1月到2021年12月。其中包括45名年龄在24-56岁之间的肥胖女性，体重指数（BMI）为34.0-48.0kg/m2。他们被随机分为两组；A组（N=22）包括接受5000IU胆钙化醇（维生素D3）补充的肥胖女性，和1000mg钙每天12个月，B组（N=23）未接受治疗。测量体重和BMI的变化及其术前体重减轻的比较，腹腔镜手术时间,并完成了住院时间。
■两组患者的传记资料没有差异。在研究期间,患者的维生素D水平增加，并且与体重减轻存在显着正相关。在A组中,平均体重减轻为11.8±3.5kg。在第一年年底，他们的BMI从基线时的36.1±1.6kg/m2下降到29.7±2.6kg/m2，而B组，平均体重减轻为6.8±3.1kg,BMI从基线时的36.9±2.69kg/m2降至32.7±0.93kg/m2.A组手术时间和住院时间均较短（107vs.128。分钟）和（3vs.5天)分别与B组相比。
■补充维生素D和钙有助于显着减轻术前肥胖女性患者的体重，这反过来又与腹腔镜腹疝修补术的效果明显更好相关。
