关键词: Animals and meta-analysis dengue systematic review virus zoonosis

来  源:   DOI:10.53854/liim-3202-7   PDF(Pubmed)

Abstract:
UNASSIGNED: Dengue is a vector-borne disease, especially important in tropical and subtropical areas. The first presentation of many arboviral diseases occurred mainly in animals, including multiple Alphaviruses and Flaviviruses, such as dengue.
UNASSIGNED: To determine the serological and molecular frequency of the dengue virus in animals.
UNASSIGNED: A systematic literature review was carried out in five databases for the proportion of animals infected with dengue, defined by molecular and serological tests. A meta-analysis was performed using a random-effects model to calculate the pooled prevalence and 95% confidence intervals (CI). Cochran?s Q test and the I2 statistic were used to assess the heterogeneity between the two studies.
UNASSIGNED: The presence of dengue in bats, primates, birds, sheep, horses, cattle, pigs, rodents and buffaloes, according to serological methods, had a prevalence of 10%, 29%, 8%, 1%, 11%, 0%, 49%, 2%, 7%, respectively. According to molecular methods, the presence of dengue in bats had a seroprevalence of 6.0%.
UNASSIGNED: The present study confirms the presence of the Dengue virus in a large group of animal species, with potential implications as possible reservoirs of this virus, raising the possibility of zoonotic transmission.
摘要:
登革热是一种媒介传播的疾病,在热带和亚热带地区尤其重要。许多虫媒病毒病的首次出现主要发生在动物身上,包括多种甲病毒和黄病毒,比如登革热。
确定登革热病毒在动物中的血清学和分子频率。
在五个数据库中对感染登革热的动物比例进行了系统的文献综述,由分子和血清学测试定义。使用随机效应模型进行荟萃分析,以计算合并的患病率和95%置信区间(CI)。Cochran?sQ检验和I2统计量用于评估两项研究之间的异质性。
蝙蝠中存在登革热,灵长类动物,鸟,绵羊,马,牛,猪,啮齿动物和水牛,根据血清学方法,患病率为10%,29%,8%,1%,11%,0%,49%,2%,7%,分别。根据分子方法,蝙蝠中登革热的血清阳性率为6.0%。
本研究证实了大量动物物种中存在登革热病毒,作为这种病毒的可能宿主,提高了人畜共患传播的可能性。
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