PDF(Pubmed)
Abstract：
China has been continuously improving its monitoring methods and strategies to address key infectious diseases (KIDs). After the severe acute respiratory syndrome epidemic in 2003, China established a comprehensive reporting system for infectious diseases (IDs) and public health emergencies. The relatively lagging warning thresholds, limited warning information, and outdated warning technology are insufficient to meet the needs of comprehensive monitoring for modern KIDs. Strengthening early monitoring and warning capabilities to enhance the public health system has become a top priority, with increasing demand for early warning thresholds, information, and techniques, thanks to constant innovation and development in molecular biology, bioinformatics, artificial intelligence, and other identification and analysis technologies. A panel of 31 experts has recommended a fourth-generation comprehensive surveillance system targeting KIDs (41 notifiable diseases and emerging IDs). The aim of this surveillance system is to systematically monitor the epidemiology and causal pathogens of KIDs in hosts such as humans, animals, and vectors, along with associated environmental pathogens. By integrating factors influencing epidemic spread and risk assessment, the surveillance system can serve to detect, predict, and provide early warnings for the occurrence, development, variation, and spread of known or novel KIDs. Moreover, we recommend comprehensive ID monitoring based on the fourth-generation surveillance system, along with a data-integrated monitoring and early warning platform and a consortium pathogen detection technology system. This series of considerations is based on systematic and comprehensive monitoring across multiple sectors, dimensions, factors, and pathogens that is supported by data integration and connectivity. This expert consensus will provides an opportunity for collaboration in various fields and relies on interdisciplinary application to enhance comprehensive monitoring, prediction, and early warning capabilities for the next generation of ID surveillance. This expert consensus will serve as a reference for ID prevention and control as well as other related activities.
摘要：
中国一直在不断改进其监测方法和策略，以应对关键传染病（KID）。在2003年严重急性呼吸系统综合症流行之后，中国建立了传染病（ID）和突发公共卫生事件的综合报告制度。相对滞后的警告阈值，有限的警告信息，和过时的警告技术不足以满足对现代KID进行全面监控的需求。加强早期监测预警能力,增强公共卫生体系已成为当务之急,随着对预警阈值的需求不断增加，信息,和技术，得益于分子生物学的不断创新和发展，生物信息学，人工智能,以及其他识别和分析技术。由31名专家组成的小组推荐了针对KID（41种应报告疾病和新出现的ID）的第四代综合监测系统。该监测系统的目的是系统地监测人等宿主中KIDs的流行病学和致病性病原体，动物,和向量，以及相关的环境病原体。通过整合影响疫情传播的因素和风险评估,监视系统可以用来检测，预测，并提供早期预警，发展,变异，以及已知或新颖的KID的传播。此外，我们建议基于第四代监控系统进行全面的身份监控，以及数据集成的监测和预警平台和联合病原体检测技术系统。这一系列考虑是基于跨多个部门的系统和全面监测,尺寸,因素，以及数据集成和连接支持的病原体。这种专家共识将为各个领域的合作提供机会，并依靠跨学科应用来加强全面监测，预测，以及下一代身份监控的预警能力。这一专家共识将作为ID预防和控制以及其他相关活动的参考。
