PDF(Pubmed)
Abstract：
UNASSIGNED: To validate the effectiveness of a gonadotropin starting dose calculator for progestin-primed ovarian stimulation (PPOS), we conducted a study comparing the outcomes of oocyte retrieval between a group assigned gonadotropin doses via the calculator and a control group, where doses were determined by the clinician\'s empirical judgment.
UNASSIGNED: Patients underwent controlled ovarian stimulation (COS) using the PPOS method, followed by oocyte retrieval. We assessed and compared the results of COS and oocyte retrieval in both groups. Additionally, we examined the concordance rate between the number of oocytes actually retrieved and the target number of oocytes in each group.
UNASSIGNED: The calculated group demonstrated a significantly higher number of preovulation follicles and a higher ovarian sensitivity index than the control group. Furthermore, the discrepancy between the target and actual number of oocytes retrieved was notably smaller in the calculated group. The concordance rate between the target and actual number of oocytes was significantly greater in the calculated group.
UNASSIGNED: The gonadotropin starting dose calculator proved to be effective within the PPOS protocol, offering a reliable method for predicting the approximate number of oocytes to be retrieved, irrespective of the COS protocol employed.
UNASSIGNED: Patients underwent controlled ovarian stimulation (COS) using the PPOS method, followed by oocyte retrieval. We assessed and compared the results of COS and oocyte retrieval in both groups. Additionally, we examined the concordance rate between the number of oocytes actually retrieved and the target number of oocytes in each group.
UNASSIGNED: The calculated group demonstrated a significantly higher number of preovulation follicles and a higher ovarian sensitivity index than the control group. Furthermore, the discrepancy between the target and actual number of oocytes retrieved was notably smaller in the calculated group. The concordance rate between the target and actual number of oocytes was significantly greater in the calculated group.
UNASSIGNED: The gonadotropin starting dose calculator proved to be effective within the PPOS protocol, offering a reliable method for predicting the approximate number of oocytes to be retrieved, irrespective of the COS protocol employed.
摘要：
■为了验证促性腺激素起始剂量计算器用于孕激素引发的卵巢刺激（PPOS）的有效性，我们进行了一项研究，比较了通过计算器分配促性腺激素剂量的组和对照组之间的卵母细胞提取结果，其中剂量由临床医生的经验判断决定。
■患者接受了使用PPOS方法的控制性卵巢刺激（COS），其次是卵母细胞检索。我们评估并比较了两组的COS和卵母细胞提取结果。此外,我们检查了各组中实际回收的卵母细胞数与目标卵母细胞数的一致率。
■与对照组相比，计算组显示出明显更高的排卵前卵泡数量和更高的卵巢敏感性指数。此外，在计算组中,目标和实际回收的卵母细胞数量之间的差异明显较小.在计算组中，目标和实际卵母细胞数之间的一致率明显更大。
■促性腺激素起始剂量计算器在PPOS方案中被证明是有效的，提供了一种可靠的方法来预测要检索的卵母细胞的大致数量，与采用的COS协议无关。
■患者接受了使用PPOS方法的控制性卵巢刺激（COS），其次是卵母细胞检索。我们评估并比较了两组的COS和卵母细胞提取结果。此外,我们检查了各组中实际回收的卵母细胞数与目标卵母细胞数的一致率。
■与对照组相比，计算组显示出明显更高的排卵前卵泡数量和更高的卵巢敏感性指数。此外，在计算组中,目标和实际回收的卵母细胞数量之间的差异明显较小.在计算组中，目标和实际卵母细胞数之间的一致率明显更大。
■促性腺激素起始剂量计算器在PPOS方案中被证明是有效的，提供了一种可靠的方法来预测要检索的卵母细胞的大致数量，与采用的COS协议无关。
