Abstract:
Acute zonal occult outer retinopathy (AZOOR) manifests as the rapid loss of one or multiple large zones of the outer retinal layers, often with a distinct sectoral distribution. Subtle fundus changes, such as pigmentary alterations around the optic nerve, are typically present in the early stages. Disease progression is characterized by the appearance of well-defined atrophic zones involving the outer retina, retinal pigment epithelium, and choroid. AZOOR lesions typically begin in the peripapillary region and then spread centrifugally toward the peripheral fundus. In this case report, we present the clinical and multimodal imaging characteristics of a 63-year-old woman with a symmetrical, peripheral-onset AZOOR variant with a very slow centrifugal progression. Most notably, the posterior pole was unaffected bilaterally.
摘要:
急性区域隐匿性外部视网膜病变(AZOOR)表现为一个或多个大区域的外部视网膜层的快速丢失。通常具有明显的部门分布。微妙的眼底变化,比如视神经周围的色素改变,通常存在于早期阶段。疾病进展的特征是出现涉及外部视网膜的定义明确的萎缩性区域,视网膜色素上皮,和脉络膜.AZOOR病变通常始于乳头周围区域,然后向周围眼底离心扩散。在这个案例报告中,我们介绍了一名63岁女性的临床和多模态影像学特征,外周起病的AZOOR变体,离心进展非常缓慢。最值得注意的是,后极两侧不受影响。