PDF(Pubmed)
Abstract：
Kimura disease (KD) is a rare chronic inflammatory disorder characterized by the development of painless subcutaneous nodules, predominantly in the head and neck region. Diagnosis relies on a high index of clinical suspicion and clinicopathological correlation, with core biopsy serving as the gold standard for a definitive diagnosis. While the disease itself is benign, it can cause significant morbidity if left untreated. This case report describes a 48-year-old male who presented with bilateral infraauricular swellings, pruritus, and elevated serum IgE levels along with eosinophilia. Imaging and histopathological correlation confirmed the diagnosis of KD. Combination therapy of corticosteroids and cyclosporine resulted in significant clinical improvement, highlighting the efficacy of the approach while avoiding surgical resection. This case emphasizes the importance of radiologic-pathologic correlation along with the use of serology to effectively diagnose KD, even in atypical presentations.
摘要：
Kimura病（KD）是一种罕见的慢性炎症性疾病，其特征是无痛性皮下结节的发展，主要在头部和颈部区域。诊断依赖于临床怀疑和临床病理相关性的高指数，核心活检作为明确诊断的金标准。虽然疾病本身是良性的，如果不及时治疗，它可能会导致严重的发病率。该病例报告描述了一名48岁的男性，他表现为双侧耳下肿胀，瘙痒,血清IgE水平升高并伴有嗜酸性粒细胞增多。影像学和组织病理学相关性证实了KD的诊断。皮质类固醇和环孢素的联合治疗导致显著的临床改善，强调该方法的疗效，同时避免手术切除。该病例强调了放射学-病理学相关性以及使用血清学来有效诊断KD的重要性。即使是在非典型的演讲中。
