PDF(Pubmed)
Abstract：
Periorbital necrotizing fasciitis (NF) is a devastating bacterial infection associated with irreversible inflammatory destruction of soft tissues. Outcomes include disfigurement, vision loss, septic shock, and death within hours to days. We describe two cases of periorbital NF that presented to our unit within a three-month period. We aim to highlight the key clinical features of periorbital NF, demonstrate the rapid progression of the disease, and the need for prompt identification and decisive intervention. Both patients presented with fever and left-sided periorbital swelling and showed rapid progression of swelling and gangrenous changes to the periorbital skin with worsening proptosis. They were treated with broad-spectrum intravenous antibiotics and underwent emergency surgical debridement of necrotic tissue followed by reconstruction. We propose a formal protocol that we recommend to aid the diagnosis and management of periorbital NF in an acute setting.
摘要：
眶周坏死性筋膜炎（NF）是一种破坏性的细菌感染，与软组织的不可逆炎症破坏有关。结果包括毁容，视力丧失,感染性休克,在几小时到几天内死亡。我们描述了在三个月内提交给我们单位的两例眶周NF。我们的目标是强调眶周NF的关键临床特征，证明了疾病的快速进展，以及需要及时识别和果断干预。两名患者均出现发烧和左侧眶周肿胀，并表现出肿胀和眶周皮肤坏疽性改变的迅速发展，并伴有眼球突出。他们接受了广谱静脉抗生素治疗，并接受了坏死组织的紧急手术清创术，然后进行了重建。我们提出了一个正式的协议，我们建议在急性环境中帮助诊断和管理眶周NF。
