PDF(Pubmed)
Abstract：
The gut microbiota has been shown to be associated with a range of illnesses and disorders, including hypertension, which is recognized as the primary factor contributing to the development of serious cardiovascular diseases. In this review, we conducted a comprehensive analysis of the progression of the research domain pertaining to gut microbiota and hypertension. Our primary emphasis was on the interplay between gut microbiota and blood pressure that are mediated by host and gut microbiota-derived metabolites. Additionally, we elaborate the reciprocal communication between gut microbiota and antihypertensive drugs, and its influence on the blood pressure of the host. The field of computer science has seen rapid progress with its great potential in the application in biomedical sciences, we prompt an exploration of the use of microbiome databases and artificial intelligence in the realm of high blood pressure prediction and prevention. We propose the use of gut microbiota as potential biomarkers in the context of hypertension prevention and therapy.
摘要：
肠道微生物群已经被证明与一系列疾病和紊乱有关，包括高血压,这被认为是导致严重心血管疾病发展的主要因素。在这次审查中,我们对与肠道菌群和高血压相关的研究领域的进展进行了全面分析.我们的主要重点是由宿主和肠道微生物群衍生的代谢产物介导的肠道微生物群和血压之间的相互作用。此外,我们阐述了肠道菌群和降压药之间的相互交流，以及它对宿主血压的影响。计算机科学领域取得了快速进展，在生物医学领域的应用潜力巨大，我们促进了微生物组数据库和人工智能在高血压预测和预防领域的应用的探索。我们建议在高血压预防和治疗的背景下使用肠道微生物群作为潜在的生物标志物。
