关键词: IPMN Mucinous cystic neoplasm Pancreas cysts Pancreatic cancer Pancreatic cystic lesions Serous cystadenoma

来  源:   DOI:10.1007/s00261-024-04337-1

Abstract:
Pancreatic cystic neoplasms are lesions comprised of cystic components that show different biological behaviors, epidemiology, clinical manifestations, imaging features, and malignant potential and management. Benign cystic neoplasms include serous cystic neoplasms (SCAs). Other pancreatic cystic lesions have malignant potential, such as intraductal papillary mucinous neoplasms and mucinous cystic neoplasms. SCAs can be divided into microcystic (classic appearance), honeycomb, oligocystic/macrocystic, and solid patterns based on imaging appearance. They are usually solitary but may be multiple in von Hippel-Lindau disease, which may depict disseminated involvement. The variable appearances of SCAs can mimic other types of pancreatic cystic lesions, and cross-sectional imaging plays an important role in their differential diagnosis. Endoscopic ultrasonography has helped in improving diagnostic accuracy of pancreatic cystic lesions by guiding tissue sampling (biopsy) or cyst fluid analysis. Immunohistochemistry and newer techniques such as radiomics have shown improved performance for preoperatively discriminating SCAs and their mimickers.
摘要:
胰腺囊性肿瘤是由表现出不同生物学行为的囊性成分组成的病变,流行病学,临床表现,成像特征,和恶性潜力和管理。良性囊性肿瘤包括浆液性囊性肿瘤(SCAs)。其他胰腺囊性病变具有恶性潜能,如导管内乳头状粘液性肿瘤和粘液性囊性肿瘤。SCA可以分为微囊(经典外观),蜂窝,少囊/大囊,和基于成像外观的固体图案。它们通常是孤立的,但在vonHippel-Lindau病中可能是多发性的,这可以描述传播的参与。SCA的各种表现可以模仿其他类型的胰腺囊性病变,横断面成像在鉴别诊断中起着重要作用。通过引导组织取样(活检)或囊肿液分析,内窥镜超声检查有助于提高胰腺囊性病变的诊断准确性。免疫组织化学和诸如放射组学之类的较新技术已显示出改善的术前区分SCA及其模拟者的性能。
公众号