Abstract：
OBJECTIVE: Obtaining a definitive pathological diagnosis from brain tissue sampling was challenging due to the small, non-representative sample. This study introduced a novel syringe technique for brain biopsy aimed at enhancing diagnostic accuracy by obtaining core tissue samples that better represent the targeted tissue.
METHODS: The ten patients with atypical brain lesions underwent the syringe biopsy. After meticulous preoperative planning with neuronavigation, a minimally invasive approach was used: a 3 cm skin incision and a 14 mm burr hole were created. A modified 3-cc syringe was used to create negative pressure and cannulate the brain tissue. The desired sample size (24 cm³) was obtained by controlling the syringe depth and withdrawal. Medical records were reviewed to assess sample analysis results and any complications RESULTS: The syringe technique successfully yielded adequate tissue samples in 9 out of 10 patients. In one case, the desired tissue could not be retrieved and required a microsurgical approach for removal. In all ten cases, a correct diagnosis was made without significant complications.
CONCLUSIONS: The preliminary findings suggest that the syringe technique is both safe and effective for obtaining substantial volumes of brain tissue, facilitating accurate pathological evaluation in cases of complex neurological disorders.
METHODS: The ten patients with atypical brain lesions underwent the syringe biopsy. After meticulous preoperative planning with neuronavigation, a minimally invasive approach was used: a 3 cm skin incision and a 14 mm burr hole were created. A modified 3-cc syringe was used to create negative pressure and cannulate the brain tissue. The desired sample size (24 cm³) was obtained by controlling the syringe depth and withdrawal. Medical records were reviewed to assess sample analysis results and any complications RESULTS: The syringe technique successfully yielded adequate tissue samples in 9 out of 10 patients. In one case, the desired tissue could not be retrieved and required a microsurgical approach for removal. In all ten cases, a correct diagnosis was made without significant complications.
CONCLUSIONS: The preliminary findings suggest that the syringe technique is both safe and effective for obtaining substantial volumes of brain tissue, facilitating accurate pathological evaluation in cases of complex neurological disorders.
摘要：
目的：从脑组织取样获得明确的病理诊断具有挑战性，不具有代表性的样本。这项研究引入了一种用于脑活检的新型注射器技术，旨在通过获得更好地代表目标组织的核心组织样本来提高诊断准确性。
方法：10例不典型脑部病变患者接受注射器活检。经过精心的术前计划和神经导航,使用微创方法:创建一个3厘米的皮肤切口和一个14毫米的毛刺孔。使用改良的3-cc注射器产生负压并插入脑组织。通过控制注射器深度和取出获得所需的样品尺寸(24cm3)。回顾了医疗记录以评估样品分析结果和任何并发症结果：注射器技术成功地在10名患者中有9名获得了足够的组织样品。在一个案例中,无法取回所需的组织，需要采用显微外科手术方法进行切除。在所有十个案例中，诊断正确,无明显并发症.
结论：初步研究结果表明，注射器技术对于获得大量的脑组织既安全又有效，在复杂的神经系统疾病的情况下促进准确的病理评估。
方法：10例不典型脑部病变患者接受注射器活检。经过精心的术前计划和神经导航,使用微创方法:创建一个3厘米的皮肤切口和一个14毫米的毛刺孔。使用改良的3-cc注射器产生负压并插入脑组织。通过控制注射器深度和取出获得所需的样品尺寸(24cm3)。回顾了医疗记录以评估样品分析结果和任何并发症结果：注射器技术成功地在10名患者中有9名获得了足够的组织样品。在一个案例中,无法取回所需的组织，需要采用显微外科手术方法进行切除。在所有十个案例中，诊断正确,无明显并发症.
结论：初步研究结果表明，注射器技术对于获得大量的脑组织既安全又有效，在复杂的神经系统疾病的情况下促进准确的病理评估。
