PDF(Pubmed)
Abstract：
BACKGROUND: Gamete and embryo donors face complex challenges affecting their health and quality of life. Healthcare providers need access to well-structured, evidence-based, and needs-based guidance to care for gamete and embryo donors. Therefore, this systematic review aimed to synthesize current assisted and third-party reproduction guidelines regarding management and care of donors.
METHODS: The databases of ISI, PubMed, Scopus, and websites of organizations related to the assisted reproduction were searched using the keywords of \"third party reproduction\", \"gamete donation\", \"embryo donation\", \"guidelines\", \"committee opinion\", and \"best practice\", without time limit up to July 2023. All the clinical or ethical guidelines and best practice statements regarding management and care for gamete and embryo donors written in the English language were included in the study. Quality assessment was carried using AGREE II tool. Included documents were reviewed and extracted data were narratively synthesized.
RESULTS: In this systematic review 14 related documents were reviewed of which eight were guidelines, three were practice codes and three were committee opinions. Five documents were developed in the United States, three in Canada, two in the United Kingdom, one in Australia, and one in Australia and New Zealand. Also, two guidelines developed by the European Society of Human Reproduction and Embryology were found. Management and care provided for donors were classified into four categories including screening, counseling, information provision, and ethical considerations.
CONCLUSIONS: While the current guidelines include some recommendations regarding the management and care of gamete/embryo donors in screening, counseling, information provision, and ethical considerations, nevertheless some shortcomings need to be addressed including donors\' psychosocial needs, long-term effects of donation, donors\' follow-up cares, and legal and human rights aspects of donation. Therefore, it is needed to conduct robust and well-designed research studies to fill the knowledge gap about gamete and embryo donors\' needs, to inform current practices by developing evidence-based guidelines.
Gamete and embryo donors face complex challenges affecting their health and quality of life. To manage these challenges, healthcare providers need guidelines that are based on evidence and donors’ real needs. In order to develop a comprehensive guideline that meets the needs of donors; it is important to review the current guidelines. So, in this study we reviewed the current assisted and third-party reproduction guidelines regarding management and care of donors. We searched databases and relevant websites and found 14 related documents. The main topics recommended for management and care of donors in these guidelines included screening, counseling, information provision, and ethical considerations. We recognized that some of donors’ needs are neglected in these documents including donors’ psychosocial needs, long-term effects of donation on donors, their follow-up cares, and legal and human rights aspects of donation. Therefore, there is need for further research to develop guidelines based on donors’ unmet needs.
METHODS: The databases of ISI, PubMed, Scopus, and websites of organizations related to the assisted reproduction were searched using the keywords of \"third party reproduction\", \"gamete donation\", \"embryo donation\", \"guidelines\", \"committee opinion\", and \"best practice\", without time limit up to July 2023. All the clinical or ethical guidelines and best practice statements regarding management and care for gamete and embryo donors written in the English language were included in the study. Quality assessment was carried using AGREE II tool. Included documents were reviewed and extracted data were narratively synthesized.
RESULTS: In this systematic review 14 related documents were reviewed of which eight were guidelines, three were practice codes and three were committee opinions. Five documents were developed in the United States, three in Canada, two in the United Kingdom, one in Australia, and one in Australia and New Zealand. Also, two guidelines developed by the European Society of Human Reproduction and Embryology were found. Management and care provided for donors were classified into four categories including screening, counseling, information provision, and ethical considerations.
CONCLUSIONS: While the current guidelines include some recommendations regarding the management and care of gamete/embryo donors in screening, counseling, information provision, and ethical considerations, nevertheless some shortcomings need to be addressed including donors\' psychosocial needs, long-term effects of donation, donors\' follow-up cares, and legal and human rights aspects of donation. Therefore, it is needed to conduct robust and well-designed research studies to fill the knowledge gap about gamete and embryo donors\' needs, to inform current practices by developing evidence-based guidelines.
Gamete and embryo donors face complex challenges affecting their health and quality of life. To manage these challenges, healthcare providers need guidelines that are based on evidence and donors’ real needs. In order to develop a comprehensive guideline that meets the needs of donors; it is important to review the current guidelines. So, in this study we reviewed the current assisted and third-party reproduction guidelines regarding management and care of donors. We searched databases and relevant websites and found 14 related documents. The main topics recommended for management and care of donors in these guidelines included screening, counseling, information provision, and ethical considerations. We recognized that some of donors’ needs are neglected in these documents including donors’ psychosocial needs, long-term effects of donation on donors, their follow-up cares, and legal and human rights aspects of donation. Therefore, there is need for further research to develop guidelines based on donors’ unmet needs.
摘要：
背景：配子和胚胎供体面临着影响其健康和生活质量的复杂挑战。医疗保健提供者需要获得结构良好、以证据为基础,以及基于需求的指导，以照顾配子和胚胎捐献者。因此,本系统综述旨在综合目前关于捐赠者管理和护理的辅助生殖指南和第三方生殖指南.
方法：ISI的数据库，PubMed,Scopus,使用“第三方生殖”关键字搜索与辅助生殖相关的组织网站，“配子捐赠”，“胚胎捐赠”，\"指南\",“委员会意见”，和“最佳实践”，没有时间限制到2023年7月。研究中包括了以英语编写的关于配子和胚胎供体的管理和护理的所有临床或伦理指南以及最佳实践声明。使用AGREEII工具进行质量评估。审查了包含的文件，并对提取的数据进行了叙述合成。
结果：在本系统综述中，对14个相关文件进行了综述，其中8个是指南，三个是执业守则，三个是委员会意见。在美国开发了五份文件，三个在加拿大,两个在英国，一个在澳大利亚,还有一个在澳大利亚和新西兰。此外，发现了欧洲人类生殖和胚胎学学会制定的两项指南。为捐助者提供的管理和护理分为四类，包括筛查，咨询,信息提供，和道德考虑。
结论：虽然目前的指南包括一些关于在筛查中配子/胚胎供体的管理和护理的建议，咨询,信息提供，和道德考虑，然而，一些缺点需要解决，包括捐助者的心理社会需求，捐赠的长期影响，捐赠者的后续护理，以及捐赠的法律和人权方面。因此,需要进行强有力和精心设计的研究，以填补有关配子和胚胎供体需求的知识空白，通过制定循证指南来告知当前的做法。配子和胚胎供体面临着影响其健康和生活质量的复杂挑战。为了应对这些挑战，医疗保健提供者需要基于证据和捐赠者实际需求的指南。为了制定满足捐助者需求的全面准则；重要的是审查当前的准则。所以,在这项研究中,我们回顾了目前关于供体管理和护理的辅助生殖指南和第三方生殖指南.我们搜索了数据库和相关网站，发现了14个相关文献。这些指南中建议管理和照顾捐赠者的主要主题包括筛查，咨询,信息提供，和道德考虑。我们认识到，这些文件忽略了一些捐助者的需求，包括捐助者的社会心理需求，捐赠对捐赠者的长期影响，他们的后续关怀，以及捐赠的法律和人权方面。因此,需要进一步研究，以根据捐助者未满足的需求制定指导方针。
方法：ISI的数据库，PubMed,Scopus,使用“第三方生殖”关键字搜索与辅助生殖相关的组织网站，“配子捐赠”，“胚胎捐赠”，\"指南\",“委员会意见”，和“最佳实践”，没有时间限制到2023年7月。研究中包括了以英语编写的关于配子和胚胎供体的管理和护理的所有临床或伦理指南以及最佳实践声明。使用AGREEII工具进行质量评估。审查了包含的文件，并对提取的数据进行了叙述合成。
结果：在本系统综述中，对14个相关文件进行了综述，其中8个是指南，三个是执业守则，三个是委员会意见。在美国开发了五份文件，三个在加拿大,两个在英国，一个在澳大利亚,还有一个在澳大利亚和新西兰。此外，发现了欧洲人类生殖和胚胎学学会制定的两项指南。为捐助者提供的管理和护理分为四类，包括筛查，咨询,信息提供，和道德考虑。
结论：虽然目前的指南包括一些关于在筛查中配子/胚胎供体的管理和护理的建议，咨询,信息提供，和道德考虑，然而，一些缺点需要解决，包括捐助者的心理社会需求，捐赠的长期影响，捐赠者的后续护理，以及捐赠的法律和人权方面。因此,需要进行强有力和精心设计的研究，以填补有关配子和胚胎供体需求的知识空白，通过制定循证指南来告知当前的做法。配子和胚胎供体面临着影响其健康和生活质量的复杂挑战。为了应对这些挑战，医疗保健提供者需要基于证据和捐赠者实际需求的指南。为了制定满足捐助者需求的全面准则；重要的是审查当前的准则。所以,在这项研究中,我们回顾了目前关于供体管理和护理的辅助生殖指南和第三方生殖指南.我们搜索了数据库和相关网站，发现了14个相关文献。这些指南中建议管理和照顾捐赠者的主要主题包括筛查，咨询,信息提供，和道德考虑。我们认识到，这些文件忽略了一些捐助者的需求，包括捐助者的社会心理需求，捐赠对捐赠者的长期影响，他们的后续关怀，以及捐赠的法律和人权方面。因此,需要进一步研究，以根据捐助者未满足的需求制定指导方针。
