Abstract:
Hydrogels are dynamically evolving 3D networks composed of hydrophilic polymer scaffolds with significant applications in the healthcare and environmental sectors. Notably, protein-based hydrogels mimic the extracellular matrix, promoting cell adhesion. Further enhancing cell proliferation within these scaffolds are matrix-metalloproteinase-triggered amino acid motifs. Integration of cell-friendly modules like peptides and proteins expands hydrogel functionality. These exceptional properties position hydrogels for diverse applications, including biomedicine, biosensors, environmental remediation, and the food industry. Despite significant progress, there is ongoing research to optimize hydrogels for biomedical and environmental applications further. Engineering novel hydrogels with favorable characteristics is crucial for regulating tissue architecture and facilitating ecological remediation. This review explores the synthesis, physicochemical properties, and biological implications of various hydrogel types and their extensive applications in biomedicine and environmental sectors. It elaborates on their potential applications, bridging the gap between advancements in the healthcare sector and solutions for environmental issues.
摘要:
水凝胶是由亲水性聚合物支架组成的动态发展的3D网络,在医疗保健和环境领域具有重要应用。值得注意的是,基于蛋白质的水凝胶模拟细胞外基质,促进细胞粘附。进一步增强这些支架内的细胞增殖的是基质金属蛋白酶触发的氨基酸基序。细胞友好模块如肽和蛋白质的整合扩展了水凝胶功能。这些特殊的性能定位水凝胶的不同应用,包括生物医学,生物传感器,环境修复,和食品工业。尽管取得了重大进展,正在进行的研究,以优化水凝胶的生物医学和环境应用进一步。工程化具有有利特性的新型水凝胶对于调节组织结构和促进生态修复至关重要。这篇综述探讨了综合,物理化学性质,以及各种水凝胶类型的生物含义及其在生物医学和环境领域的广泛应用。它详细阐述了它们的潜在应用,弥合医疗保健领域的进步与环境问题解决方案之间的差距。本文受版权保护。保留所有权利。