PDF(Pubmed)
Abstract：
BACKGROUND: Spinal surgery is a common procedure associated with significant postoperative pain, and identifying effective interventions to manage this pain is crucial for optimizing patient outcomes. This review assesses the existing literature to determine the overall impact of vitamin C supplementation on spinal postoperative pain. Vitamin C, also known as ascorbic acid, is an essential nutrient that plays a vital role in numerous physiological processes. It functions as a potent antioxidant, neutralizing free radicals and reducing oxidative stress within the body. Furthermore, vitamin C is a cofactor in collagen synthesis, a crucial component of connective tissues, including those found in the spinal structures. Given its antioxidant and collagen-promoting properties, vitamin C has piqued interest as a potential therapeutic option for postoperative spinal pain. Based on the available evidence, vitamin C may have a beneficial effect on postoperative spinal pain, including reducing pain scores, analgesic consumption, and the incidence of complications such as complex regional pain syndrome. However, more research is needed to fully understand the optimal dosage and duration of vitamin C supplementation for postoperative pain management.
CONCLUSIONS: Vitamin C could be considered a potentially beneficial adjunctive therapy for managing spinal postoperative pain, but its routine use requires further investigation.
CONCLUSIONS: Vitamin C could be considered a potentially beneficial adjunctive therapy for managing spinal postoperative pain, but its routine use requires further investigation.
摘要：
背景：脊柱手术是与术后明显疼痛相关的常见手术，确定有效的干预措施来管理这种疼痛对于优化患者治疗效果至关重要.这篇综述评估了现有文献，以确定补充维生素C对脊柱术后疼痛的总体影响。维生素C,也被称为抗坏血酸，是一种必需的营养素，在许多生理过程中起着至关重要的作用。它作为一种有效的抗氧化剂，中和自由基，减少体内的氧化应激。此外，维生素C是胶原蛋白合成的辅助因子，结缔组织的重要组成部分，包括在脊柱结构中发现的那些。鉴于其抗氧化和胶原蛋白促进特性，维生素C作为术后脊柱疼痛的潜在治疗选择引起了人们的兴趣.根据现有证据,维生素C可能对术后脊柱疼痛有有益作用，包括降低疼痛评分,镇痛消耗，以及复杂区域疼痛综合征等并发症的发生率。然而,需要更多的研究来充分了解用于术后疼痛管理的维生素C补充剂的最佳剂量和持续时间.
结论：维生素C可被认为是治疗脊柱术后疼痛的潜在有益辅助治疗，但是它的常规使用需要进一步调查。
结论：维生素C可被认为是治疗脊柱术后疼痛的潜在有益辅助治疗，但是它的常规使用需要进一步调查。
