Abstract：
OBJECTIVE: The purpose of this study was to evaluate the outcomes of the sentinel node navigation surgery (SNNS) followed by limited gastrectomy for early gastric cancer (EGC) with Endoscopic Curability C-2 (eCuraC-2).
METHODS: Between 2001 and 2018, 33 patients were included in this study. Following sentinel node (SN) biopsy using indocyanine green combined with an infrared ray laparoscopic system, limited gastrectomy (LG) [wedge resection (WR), or segmental gastrectomy (SG)] was performed without extended lymphadenectomy.
RESULTS: SN detection rate was 97% (32/33). The mean number of SNs per case was 7.8. Three patients (9.1%) with lymph node metastasis (LNM) had a positive SN identified by intraoperative pathological examination. When intraoperative pathologic examination showed SN to be LNM negative, 11 patients underwent WR, and seven were subjected to SG. Postoperative pathological examinations showed no false negatives for LNM, and four patients (12%) had residual cancer in their resected stomachs. Overall survival and disease-specific survival five years after SNNS were 87.9% and 100%, respectively.
CONCLUSIONS: SNNS followed by LG with lymphatic basin resection may be one of the ideal procedures for patients with eCuraC-2 due to the accurate diagnosis of LNM and favorable disease-specific prognosis.
METHODS: Between 2001 and 2018, 33 patients were included in this study. Following sentinel node (SN) biopsy using indocyanine green combined with an infrared ray laparoscopic system, limited gastrectomy (LG) [wedge resection (WR), or segmental gastrectomy (SG)] was performed without extended lymphadenectomy.
RESULTS: SN detection rate was 97% (32/33). The mean number of SNs per case was 7.8. Three patients (9.1%) with lymph node metastasis (LNM) had a positive SN identified by intraoperative pathological examination. When intraoperative pathologic examination showed SN to be LNM negative, 11 patients underwent WR, and seven were subjected to SG. Postoperative pathological examinations showed no false negatives for LNM, and four patients (12%) had residual cancer in their resected stomachs. Overall survival and disease-specific survival five years after SNNS were 87.9% and 100%, respectively.
CONCLUSIONS: SNNS followed by LG with lymphatic basin resection may be one of the ideal procedures for patients with eCuraC-2 due to the accurate diagnosis of LNM and favorable disease-specific prognosis.
摘要：
目的：本研究的目的是评估前哨淋巴结导航手术（SNNS）后有限胃切除术治疗早期胃癌（EGC）的疗效。
方法：在2001年至2018年之间，本研究纳入了33例患者。使用吲哚菁绿结合红外线腹腔镜系统进行前哨淋巴结（SN）活检后，有限胃切除术（LG）[楔形切除术（WR），或节段胃切除术（SG）]未进行扩展淋巴结切除术。
结果：SN检出率为97%(32/33)。每个病例的平均SNs数为7.8。3例（9.1％）淋巴结转移（LNM）患者术中病理检查发现SN阳性。当术中病理检查显示SN为LNM阴性时，11例患者接受WR，七个人接受了SG。术后病理检查无LNM假阴性,4例患者（12%）在切除的胃中残留癌症。SNNS后5年的总生存率和疾病特异性生存率分别为87.9%和100%。分别。
结论：SNNS后加LG淋巴盆切除术可能是eCuraC-2患者的理想手术之一，因为LNM的诊断准确，疾病特异性预后良好。
方法：在2001年至2018年之间，本研究纳入了33例患者。使用吲哚菁绿结合红外线腹腔镜系统进行前哨淋巴结（SN）活检后，有限胃切除术（LG）[楔形切除术（WR），或节段胃切除术（SG）]未进行扩展淋巴结切除术。
结果：SN检出率为97%(32/33)。每个病例的平均SNs数为7.8。3例（9.1％）淋巴结转移（LNM）患者术中病理检查发现SN阳性。当术中病理检查显示SN为LNM阴性时，11例患者接受WR，七个人接受了SG。术后病理检查无LNM假阴性,4例患者（12%）在切除的胃中残留癌症。SNNS后5年的总生存率和疾病特异性生存率分别为87.9%和100%。分别。
结论：SNNS后加LG淋巴盆切除术可能是eCuraC-2患者的理想手术之一，因为LNM的诊断准确，疾病特异性预后良好。
